41995-30-6

Basic information

• Product Name: 3,5-dimethylpyridin-2-amine
• Synonyms: 3,5-dimethylpyridin-2-amine;2-Amino-3,5-dimethylpyridine;3,5-Dimethyl-2-pyridinamine;2-PyridinaMine, 3,5-diMethyl-;2-Amino-3,5-dimethylpyridine≥ 99% (HPLC)
• CAS NO: 41995-30-6
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.1677
• EINECS: 255-613-8
• Mol File: 41995-30-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 239.9 °C at 760 mmHg
• Flash Point: 122 °C
• Appearance: /
• Density: 1.039g/cm³
• Vapor Pressure: 0.0392mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 3,5-dimethylpyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethylpyridin-2-amine(41995-30-6)
• EPA Substance Registry System: 3,5-dimethylpyridin-2-amine(41995-30-6)

Safety Data

• Hazardous Substances Data: 41995-30-6(Hazardous Substances Data)

Usage

Description

3,5-Dimethylpyridin-2-amine is an organic compound with the chemical formula C7H10N2. It is a derivative of pyridine, featuring two methyl groups at the 3rd and 5th positions and an amino group at the 2nd position. 3,5-dimethylpyridin-2-amine is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
3,5-Dimethylpyridin-2-amine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of drugs targeting specific enzymes or receptors.
Used in Chemical Research:
3,5-Dimethylpyridin-2-amine is used as a research compound in the evaluation of substituted 2-aminopyridines as inhibitors of nitric oxide synthases. This application is crucial for understanding the compound's potential as a therapeutic agent and its interactions with biological systems.
Used in the Synthesis of Pesticides:
3,5-Dimethylpyridin-2-amine can be utilized as a building block in the synthesis of pesticides, particularly those targeting specific pests while minimizing harm to the environment and non-target organisms.
Used in Material Science:
3,5-dimethylpyridin-2-amine may also find applications in material science, where it can be used to develop new materials with unique properties, such as improved conductivity or enhanced stability.

InChI:InChI=1/C7H10N2/c1-5-3-6(2)7(8)9-4-5/h3-4H,1-2H3,(H2,8,9)

Upstream product

• 591-22-0 3,5-Lutidine 
• 3718-65-8 3,5-Dimethylpyridine N-oxide 
• 92992-85-3 2-bromine-3,5-dimethylpyridine 
• 64-17-5 ethanol 

Downstream Products

• 1356000-38-8 {1-[4-(6,8-dimethyl-3-phenyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester 
• 117846-58-9 2,6-dibromo-3,5-dimethylpyridine 

Relevant articles and documents

Catalyst-free synthesis of substituted pyridin-2-yl, quinolin-2-yl, and isoquinolin-1-yl carbamates from the corresponding hetaryl ureas and alcohols

A novel catalyst-free synthesis ofN-pyridin-2-yl,N-quinolin-2-yl, andN-isoquinolin-1-yl carbamates utilizes easily accessibleN-hetaryl ureas and alcohols. The proposed environmentally friendly technique is suitable for the good-to-high yielding synthesis of a wide range ofN-pyridin-2-yl orN-quinolin-2-yl substituted carbamates featuring electron-donating and electron-withdrawing groups in the azine rings and containing various primary, secondary, and even tertiary alkyl substituents at the oxygen atom (48-94%; 31 examples). The DFT calculation and experimental study showed that the reaction proceeds through the intermediate formation of hetaryl isocyanates. The method can be applied to obtainN-isoquinolin-1-yl carbamates, although in lower yields, and ethyl benzo[h]quinolin-2-yl carbamate has also been successfully synthesized (68%).

NOVEL COMPOUNDS

The present invention is directed to novel retinoid-related orphan receptor gamma (RORγ) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by RORγ.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthases.

A series of substituted 2-aminopyridines was prepared and evaluated as inhibitors of human nitric oxide synthases (NOS). 4,6-Disubstitution enhanced both potency and specificity for the inducible NOS with the most potent compound having an IC50 of 28 nM.