421-57-8

Basic information

• Product Name: dimethyl(trifluoromethyl)phosphane
• Synonyms: Phosphine, dimethyl(trifluoromethyl)-
• CAS NO: 421-57-8
• Molecular Formula: C₃H₆F₃P
• Molecular Weight: 130.0487
• Mol File: 421-57-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 33.8°C at 760 mmHg
• Vapor Pressure: 555mmHg at 25°C
• CAS DataBase Reference: dimethyl(trifluoromethyl)phosphane(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl(trifluoromethyl)phosphane(421-57-8)
• EPA Substance Registry System: dimethyl(trifluoromethyl)phosphane(421-57-8)

Safety Data

• Hazardous Substances Data: 421-57-8(Hazardous Substances Data)

Upstream product

• 2314-97-8 iodotrifluoromethane 
• 594-09-2 trimethylphosphane 
• 1605-54-5 methyl-bis-trifluoromethyl-phosphine 
• 74-88-4 methyl iodide 

Relevant articles and documents

Advances in trifluoromethylating phosphorus compounds

The System CF3IMe3P is re-investigated and Me2PCF3, Me4P+I-, (CF3)2PMe3, Me3PI2, [Me3(CF3)P]+I- are found as products. Using CF3Br/P(NEt2)3 the phosphines R12PCF3 and R1P(CF3)2 (e.g. R1 = Me, iPr, NEt2) can be obtained which are precursors either for phosphoranes (e.g. 1,2λ5σ5-oxaphosphetanes) or phosphonium salts (e.g. [R12(Me)PCF3]+X- or [R1(Me)P(CF3)2X-]. The latter are deprotonated to furnish methylene phosphoranes R12(CH2=)PCF3 or R1(CH2=)P(CF3)2, reactive synthons. From CF3Br/ P(NEt2)3/P(OPh)3 the phosphine P(CF3)3 is available, which turned out to be a potent electrophile. Amido phospites ROP(NEt2)2 and halides R2X (R2= CCl2CF3, X= Cl; R2= CF=CFCF3, X= F; R2= C6F5, X= Br, I; R2= C(CF3)3, X= Br; R2= SCF3, X= CF3) undergo an ARBUZOV reaction.