42104-70-1

Basic information

• Product Name: N,N-Tetramethyleneacrylamide
• Synonyms: 1-(1-Pyrrolidinyl)-2-propene-1-one;1-Acryloylpyrrolidine;1-Pyrrolizino-2-propene-1-one;N,N-Tetramethyleneacrylamide;1-(1-pyrrolidinyl)-2-Propen-1-one
• CAS NO: 42104-70-1
• Molecular Formula: C₇H₁₁NO
• Molecular Weight: 125.17
• Mol File: 42104-70-1.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N-Tetramethyleneacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Tetramethyleneacrylamide(42104-70-1)
• EPA Substance Registry System: N,N-Tetramethyleneacrylamide(42104-70-1)

Safety Data

• Hazardous Substances Data: 42104-70-1(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 814-68-6 acryloyl chloride 
• 625-36-5 2-chloropropionyl chloride 
• 74-86-2 acetylene 
• 92-84-2 10H-phenothiazine 
• 4553-05-3 1-pyrrolidin-1-yl-propan-1-one 
• 79-10-7 acrylic acid 

Downstream Products

• 72299-21-9 3-Cyclohexyl-1-pyrrolidin-1-yl-propan-1-one 
• 20681-51-0 methyl 3-cyclohexylpropionate 
• 119163-30-3 Oxiranyl-pyrrolidin-1-yl-methanone 
• 725697-51-8 [3-(4-chlorophenyl)-4,5-dihydro-isoxazol-5-yl]pyrrolidin-1-yl-methanone 
• 1009337-76-1 (3-phenyl-4,5-dihydroisoxazol-5-yl)(pyrrolidin-1-yl)methanone 
• 78910-33-5 sarmentine 
• 1353779-67-5 C₂₉H₄₁NO₃Si 
• 1448245-29-1 (5S,7aR)-(-)-[7a-methyl-2-(toluene-4-sulfonyl)-2,3,5,6,7,7a-hexahydro-1H-isoindol-5-yl]pyrrolidin-1-yl-methanone 
• 1448245-43-9 (3aS,5S,7aR)-(-)-[7a-methyl-2-(toluene-4-sulfonyl)octahydroisoindol-5-yl]pyrrolidin-1-yl-methanone 
• 1442644-18-9 tert-butyl (2R,4R)-5,5-diphenyl-4-(pyrrolidine-1-carbonyl)pyrrolidine-2-carboxylate 

Relevant articles and documents

METHOD OF PRODUCING ACRYLOYL MONOMERS AND ACRYLOYL-BASED POLYMERS

Embodiments of the present disclosure are directed to a method of making a reaction inhibiting polymer having a formula of M-CO-NR. The method may comprise reacting PAA with an organic coupling reagent and at least one alicyclic amine to produce the reaction inhibiting polymer. In accordance with another embodiment of the present disclosure, a method of making an acryloyl monomer having a formula of R?a#191-CO-NR may comprise reacting an acrylic acid with an organic coupling reagent and an alicyclic amine to form the acryloyl monomer. R?a#191 may be an alkylene moiety, M may be a poly(acrylic) acid backbone. NR may be an alicyclic amine moiety coupled to the polymer backbone or coupled to the alkylene moiety.

Radical α,β-Dehydrogenation of Saturated Amides via α-Oxidation with TEMPO under Transition Metal-Free Conditions

A transition metal-free radical process for the selective α,β-dehydrogenation of saturated amides under mild conditions is developed. Utilizing radical activation strategy, the challenging issue associated with the low α-acidity of amides is resolved. For the first time, α,β-unsaturated Weinreb amides and acrylamides could be efficiently prepared directly from corresponding saturated amides. Mechanistic studies confirm the radical nature of this transformation. Two gram scale α,β-dehydrogenation have also been performed to demonstrate the utility of this method.

COMPOSITONS AND METHODS FOR MODULATING UBA5

Disclosed herein, inter alia, are compositions and methods useful for inhibiting ubiquitin-like modifier activating enzyme 5.