42105-26-0

Basic information

• Product Name: 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE
• Synonyms: 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE;3-BUTYN-2-AMINE HYDROCHLORIDE;3-Butyn-2-amine, hydrochloride (9CI);but-3-yn-2-amine hydrochloride
• CAS NO: 42105-26-0
• Molecular Formula: C₄H₇N*ClH
• Molecular Weight: 105.56602
• Mol File: 42105-26-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 132.4 °C at 760 mmHg
• Flash Point: 33.9 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE(42105-26-0)
• EPA Substance Registry System: 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE(42105-26-0)

Safety Data

• Hazardous Substances Data: 42105-26-0(Hazardous Substances Data)

Usage

General Description

1-Methyl-prop-2-ynylamine hydrochloride is a chemical compound with the molecular formula C4H8ClN. It is a white to off-white crystalline powder that is soluble in water. 1-METHYL-PROP-2-YNYLAMINE HYDROCHLORIDE is used as a building block in the synthesis of pharmaceuticals and agrochemicals. It can also be used as a reactant in the production of other chemicals such as pesticides and herbicides. 1-Methyl-prop-2-ynylamine hydrochloride is considered to be a hazardous substance and should be handled with care, following proper safety protocols and guidelines.

Upstream product

• 59967-06-5 1-methylprop-2-ynyl methanesulfonate 
• 14396-89-5 2-(1-methylprop-2-ynyl)-1H-isoindole-1,3(2H)-dione 

Downstream Products

• 61448-33-7 N-<(S)-1-methyl-2-propynyl>-(R)-O-methylmandelic amide 
• 61448-32-6 N-<(R)-1-methyl-2-propynyl>-(R)-O-methylmandelic amide 
• 1422561-07-6 C₂₂H₂₉N₃O₅ 
• 491879-61-9 4-methyl-N-(1-methylprop-2-ynyl)-benzenesulfonamide 
• 30389-17-4 but-3-yn-2-amine 
• 10354-14-0 2,3-dimethyl-4-phenylpyridine 

Relevant articles and documents

1-((1H-PYRAZOL-4-YL)METHYL)-3-(PHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS GPR139 ANTAGONISTS FOR THE TREATMENT OF E.G. DEPRESSION

The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease

Synthesis and bioactivities of novel N-(4-(2-Aryloxythiazol-5-yl)but-3-yn- 2-yl)benzamides

A series of novel N-(4-(2-aryloxythiazol-5-yl)but-3-yn-2-yl)benzamide derivatives were designed and synthesized. Their structures were identified by 1H NMR and elemental analyses. Preliminary bioassays indicated that some title compounds provided >80% control of Sclerotinia sclerotiorum at 50 μg/mL and >70% herbicidal activities against B. campestris at 100 μg/mL. Their structure-activities relationships were also discussed. A series of novel N-(4-(2-aryloxythiazol-5-yl)but-3-yn-2-yl)benzamide derivatives were designed and synthesized. Some of them provided >80% control of Sclerotinia sclerotiorum at 50 μg/mL and >70% herbicidal activities against B. campestris at 100 μg/mL. Copyright

Psychoactive propargylamine derivatives used in the treatment of anxiety, psychotic states or aggression

Propargylamine derivatives having the general formula: STR1 wherein R is a hydrogen atom, an unsubstituted phenyl group or a phenyl group substituted with halogen, trifluoromethyl, loweralkoxy, nitro, cyano, amido or N,N-diloweralkylamido, R1,