42116-86-9

Basic information

• Product Name: Phosphonium, (1,3-dihydro-3-oxo-1-isobenzofuranyl)triphenyl-, bromide
• CAS NO: 42116-86-9
• Molecular Formula: C26H20O2P.Br
• Molecular Weight: 475.321
• Mol File: 42116-86-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phosphonium, (1,3-dihydro-3-oxo-1-isobenzofuranyl)triphenyl-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonium, (1,3-dihydro-3-oxo-1-isobenzofuranyl)triphenyl-, bromide(42116-86-9)
• EPA Substance Registry System: Phosphonium, (1,3-dihydro-3-oxo-1-isobenzofuranyl)triphenyl-, bromide(42116-86-9)

Safety Data

• Hazardous Substances Data: 42116-86-9(Hazardous Substances Data)

Upstream product

• 6940-49-4 3-Bromophthalide 
• 603-35-0 triphenylphosphine 
• 119-67-5 o-carboxybenzaldehyde 
• 87-41-2 2-benzofuran-1(3H)-one 

Downstream Products

• 574008-35-8 4-[4-(benzyloxy)butyl]-1(2H)-phthalazinone 
• 1217472-04-2 1-(4-benzyloxybenzyl)-4-chlorophthalazine 
• 1196046-93-1 3-(5-chloro-2-nitrobenzylidene)-2-benzofuran-1(3H)-one 
• 127223-36-3 2,2'-Bis-[2-(3-methoxy-phenyl)-ethyl]-[2,2']biindenyl-1,3,1',3'-tetraone 
• 127223-29-4 2-<2-(3-methoxyphenyl)ethyl>-1,3-indanedione 
• 127223-35-2 2,3-dihydro-7-benzyloxy-1H-indene-1-spiro-2'-(2H-indene)-1',3'-dione 
• 127223-30-7 2-<2-(3-benzyloxyphenyl)ethyl>-1,3-indanedione 
• 127223-34-1 2,2'-Diphenethyl-[2,2']biindenyl-1,3,1',3'-tetraone 
• 80792-90-1 2-<2-(phenyl)ethyl>-1,3-indanedione 
• 114259-22-2 o-<(p-nitrophenyl)acetyl>benzoic acid 
• 171598-15-5 cinnamylidene-phthalide 
• 574008-40-5 4-(5-benzyloxy-pentyl)-2H-phthalazin-1-one 

Relevant articles and documents

NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS

The present invention provides novel poly(ADP-ribose) polymerase (PARP) inhibitors, methods of preparing them, pharmaceutical compositions containing them and methods for the treatment, prevention and/or amelioration of PARP mediated diseases or disorders using them. In particular, the compounds described herein are useful for the treatment of carcinoma of the breast, ovarian cancer, carcinoma of the liver, carcinoma of the lung, small cell lung cancer, esophageal cancer, gall bladder cancer, pancreatic cancer and stomach cancer.

SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION

Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof. R1 is independently hydrogen or (C1-C6)alkyl; R2 is independently hydrogen, (C1-C6)alkyl, aryl, or heteroaryl; R2' is independently hydrogen, (C1-C6)alkyl, CF3 or C2F5; R3 is independently (C1-C6)alkyl, aryl, 2-tetrahydrofuryhnethyl, an aliphatic tertiary amine, or 4-methoxybenzyl; or R2 and R3 may be joined together to form a 5 or 6 member ring lactone; R4 is independently hydrogen, (C1-C6)alkyl, a 2- or 4-R5-substituted aromatic ring selected from a 4-R5-phenyl or a 2-R5-5-pyridyl, aryl, heteroaryl, aliphatic tertiary amine or halogen; and R5, R5', R6, R6', R7, R7' are each independently hydrogen, (C1-C6)alkyl, aryl, optionally substituted phenyl, heteroaryl, a heterocyclic ring, an aliphatic tertiary amine, or halogen.

Radical mediated reactions in organic synthesis

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