42164-79-4

Basic information

• Product Name: α-Hydroxy-3-nitrobenzeneacetic acid
• Synonyms: α-Hydroxy-3-nitrobenzeneacetic acid;2-hydroxy-2-(3-nitrophenyl)acetic acid
• CAS NO: 42164-79-4
• Molecular Formula: C₈H₇NO₅
• Molecular Weight: 197.14488
• Mol File: 42164-79-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 405.3°C at 760 mmHg
• Flash Point: 183.1°C
• Appearance: /
• Density: 1.552g/cm³
• Vapor Pressure: 2.7E-07mmHg at 25°C
• Refractive Index: 1.634
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: α-Hydroxy-3-nitrobenzeneacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: α-Hydroxy-3-nitrobenzeneacetic acid(42164-79-4)
• EPA Substance Registry System: α-Hydroxy-3-nitrobenzeneacetic acid(42164-79-4)

Safety Data

• Hazardous Substances Data: 42164-79-4(Hazardous Substances Data)

Usage

General Description

α-Hydroxy-3-nitrobenzeneacetic acid is a chemical compound that belongs to the class of organic compounds known as nitrobenzoic acids. It is a yellow solid with the molecular formula C8H7NO5 and a molecular weight of 197.147 g/mol. It is a derivative of 3-nitrobenzoic acid and contains a hydroxy group and a carboxylic acid group on the benzene ring. α-Hydroxy-3-nitrobenzeneacetic acid is often used in organic synthesis and as a building block in the preparation of various pharmaceuticals and agrochemicals due to its versatile reactivity and functional groups. Additionally, it has potential applications in the field of materials science and can be used as a starting material for the synthesis of various specialty chemicals.

InChI:InChI=1/C8H7NO5/c10-7(8(11)12)5-2-1-3-6(4-5)9(13)14/h1-4,7,10H,(H,11,12)

Upstream product

• 6890-77-3 3-nitrophenylglyoxal 
• 13651-07-5 2,2-dibromo-1-(3-nitrophenyl)ethan-1-one 
• 13312-82-8 3-nitro-mandelonitrile 
• 13312-88-4 meta nitromandelic acid ethyl ester 
• 30077-08-8 d-α-amino-m-nitrophenylacetic acid 
• 151-50-8 potassium cyanide 
• 99-61-6 3-nitro-benzaldehyde 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 7677-24-9 trimethylsilyl cyanide 
• 2835-06-5 phenylglycin 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 93555-01-2 2-(3-nitrophenyl)-2-[(trimethylsilyl)oxy]acetonitrile 

Downstream Products

• 52944-27-1 (R,S)-2-hydroxy-2-(3-aminophenyl)acetic acid 
• 92057-09-5 ethyl 2-(3-nitrophenyl)-2-oxoacetate 
• 97522-68-4 anhydro-2-(3-nitrophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 6330-40-1 2-(3-nitrophenyl)-2-oxoacetic acid 
• 99-61-6 3-nitro-benzaldehyde 
• 75172-64-4 (R)-(-)-3-nitromandelic acid 
• 602301-53-1 (S)-Acetoxy-(3-nitro-phenyl)-acetic acid 
• 75172-60-0 (S)-(+)-3-nitromandelic acid 
• 97522-70-8 anhydro-2-(3-aminophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 97522-72-0 anhydro-2-(3-acetamidophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 17430-90-9 (RS)-methoxy-(3-nitro-phenyl)-acetic acid methyl ester 
• 1173294-94-4 (3-nitrophenyl)(2-(pyridin-2-yl)phenyl)methanone 
• 5496-38-8 2-(3-nitrophenyl)-4,5-diphenyl-1H-imidazole 

Relevant articles and documents

Enzymatic resolution of substituted mandelic acids

A series of substituted mandelic acids were prepared and subjected to enzymatic resolution utilizing Lipase PS 'Amano'.

7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives

7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives containing blocking groups on the α-hydroxy group and their nontoxic, pharmaceutically acceptable salts are valuable as antibacterial agents and are particularly valuable as therapeutic agents in poultry and in animals, including man, in the treatment of infectious diseases caused by many Gram-positive and Gram-negative bacteria. A preferred compound is 7-(D-mandelamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acid.