422517-67-7 Usage
General Description
1-(4-Nitrobenzyl)piperazine dihydrochloride is a chemical compound that is often used as a building block in the synthesis of pharmaceuticals. It is a derivative of piperazine, a heterocyclic compound commonly found in drugs and pesticides. The addition of a 4-nitrobenzyl group to the piperazine molecule increases its reactivity and can lead to new and improved drugs with enhanced pharmacological properties. The dihydrochloride form of this compound indicates that it is in a salt form, which can improve its stability and solubility in aqueous environments. Overall, 1-(4-Nitrobenzyl)piperazine dihydrochloride is an important intermediate in the synthesis of pharmaceuticals and has potential applications in the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 422517-67-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,2,5,1 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 422517-67:
(8*4)+(7*2)+(6*2)+(5*5)+(4*1)+(3*7)+(2*6)+(1*7)=127
127 % 10 = 7
So 422517-67-7 is a valid CAS Registry Number.
422517-67-7Relevant articles and documents
Aralkyl-alcohol peiperazine derivatives adn their uses as antidepressant
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Page/Page column 8, (2008/06/13)
Aryl alkanol piperazine derivatives of the formula and pharmaceutical compositions comprising the same. Also disclosed are methods for treating depression using the pharmaceutical compositon. Compounds of the invention have excellent dual inhibitory actions to the uptake of the mono-amines neurotransmitter, good antidepressant activities and minor side effects.
Substituted indolinones, preparation thereof and their use as pharmaceutical compositions
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, (2008/06/13)
Indolinones of general formula I which are inhibitors of cell proliferation, particularly of tumour cells, and inhibitors of protein kinases. The following compounds are exemplary: (Z)-3-{1-[4-(N-(2-aminoethyl)-N-methylsulphonyl-amino)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone, (Z)-3-{1 -[4-(N-(2-dimethylaminoethyl)-N-phenylsulphonyl-amino)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone, and (Z)-3-{1-[4-(4-methylpiperazinomethyl)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone.