422569-56-0

Basic information

• Product Name: 3,5-bis(3-hydroxyprop-1-ynyl)benzaldehyde
• Synonyms: 3,5-bis(3-hydroxyprop-1-ynyl)benzaldehyde
• CAS NO: 422569-56-0
• Molecular Weight: 214.221
• Mol File: 422569-56-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-bis(3-hydroxyprop-1-ynyl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(3-hydroxyprop-1-ynyl)benzaldehyde(422569-56-0)
• EPA Substance Registry System: 3,5-bis(3-hydroxyprop-1-ynyl)benzaldehyde(422569-56-0)

Safety Data

• Hazardous Substances Data: 422569-56-0(Hazardous Substances Data)

Upstream product

• 145691-59-4 (3,5-dibromophenyl)methanol 
• 618-58-6 3,5-dibromobenzoic acid 
• 56990-02-4 3,5-dibromobenzaldehyde 
• 107-19-7 propargyl alcohol 

Relevant articles and documents

An improved sonogashira coupling procedure for the construction of rigid aromatic multifunctional monomers bearing 1,3-substituted acetylenic units

The efficient synthesis of rigid multifunctional vinylic monomers 1 and 2 from 3,5-dibromobenzene derivatives and propargyl alcohol via the Sonogashira reaction is reported. For example, a series of 3,5-bis(3-hydroxyprop-1-ynl)benzoate ester derivatives have been prepared efficiently using an improved palladium catalyst system. Subsequent hydrolysis and reaction with 4-vinylaniline afforded a new monomer 2 for use in functional macroporous polymer systems. In addition, Sonogashira and Wittig methodologies have been optimised in order to construct successfully an alternative rigid monomer 1 from 3,5-dibromobenzaldehyde.