42397-64-8 Usage
Chemical Properties
solid
Uses
There is no evidence that 1,6-dinitropyrene has been used for any commercial purpose (IARC 1989). 1,6-Dinitropyrene is available for research purposes at a purity of 98% or higher. It is also available in 14C- or 3H-labeled form at a radiochemical purity of 98% or higher.
General Description
1,6-Dinitropyrene is a potent mutagenic components of diesel exhaust and air pollutant. 1,6-Dinitropyrene is an extremely potent genotoxicant in metabolically competent primary cultures of human and rat hepatocytes.
Reactivity Profile
Aromatic nitro compounds, such as 1,6-DINITROPYRENE, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition, 1,6-DINITROPYRENE emits toxic fumes of NOx.
Fire Hazard
Flash point data for 1,6-DINITROPYRENE are not available; however 1,6-DINITROPYRENE is probably combustible.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic data. Human
mutation data reported. When heated to
decomposition it emits toxic fumes of NOx
Carcinogenicity
1,6-Dinitropyrene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Check Digit Verification of cas no
The CAS Registry Mumber 42397-64-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,3,9 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 42397-64:
(7*4)+(6*2)+(5*3)+(4*9)+(3*7)+(2*6)+(1*4)=128
128 % 10 = 8
So 42397-64-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H8N2O4/c19-17(20)13-8-4-10-2-6-12-14(18(21)22)7-3-9-1-5-11(13)16(10)15(9)12/h1-8H
42397-64-8Relevant articles and documents
Preparation of Pure Isomers of Dinitropyrenes
Hashimoto, Yuichi,Shudo, Koichi
, p. 1992 - 1994 (2007/10/02)
Isomers of dinitripyrenes (1,3-, 1,6-, and 1,8-dinitripyrenes) uncontamined by the other isomers were prepared from the corresponding diaminopyrenes by oxidation, or nucleophilic substitution with nitrite after diazotization.Keywords: dinitropyrene; 1,3-dinitropyrene; 1,6-dinitropyrene; 1,8-dinitropyrene; diaminopyrene; preparation of nitroarenes.
