42473-89-2

Basic information

• Product Name: 1-(3,4-dichloro-phenyl)-propane-1,2-dione-1-oxime
• Synonyms: 1-(3,4-dichloro-phenyl)-propane-1,2-dione-1-oxime
• CAS NO: 42473-89-2
• Molecular Weight: 232.066
• Mol File: 42473-89-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dichloro-phenyl)-propane-1,2-dione-1-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dichloro-phenyl)-propane-1,2-dione-1-oxime(42473-89-2)
• EPA Substance Registry System: 1-(3,4-dichloro-phenyl)-propane-1,2-dione-1-oxime(42473-89-2)

Safety Data

• Hazardous Substances Data: 42473-89-2(Hazardous Substances Data)

Upstream product

• 6097-32-1 1-(3,4-dichlorophenyl)propanone 

Downstream Products

• 90726-26-4 1-amino-1-cyclohexyl-propan-2-ol 

Relevant articles and documents

2-AMINOOXAZOLINES AS TAAR1 LIGANDS

The invention relates to compounds of formula (I) wherein R1 is halogen; R2 is lower alkyl or lower alkyl substituted by halogen; R2' is hydrogen, lower alkyl or lower alkyl substituted by halogen; X is a bond, -CH2-, -CH2CH2- or -CH2CH2CH2-; Y is phenyl or cyclohexyl; and n is 0, 1 or 2; or to a pharmaceutically suitable acid addition salt thereof. The compounds of formula I are active on the TAAR1 receptor and are therefore suitable for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.