42498-38-4

Basic information

• Product Name: 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE
• Synonyms: 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE;4-Bromo-N-(tert-butyl)benzamide 98%;4-bromo-N-tert-butylbenzamide;N-t-Butyl 4-bromobenzamide;N-tert-Butyl-4-bromobenzamide;4-Bromo-N-(tert-butyl)benzamide98%
• CAS NO: 42498-38-4
• Molecular Formula: C₁₁H₁₄BrNO
• Molecular Weight: 256.14
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 42498-38-4.mol
• Article Data: 31

Chemical Properties

• Melting Point: 134.98 °C
• Boiling Point: 350.5°Cat760mmHg
• Flash Point: 165.8°C
• Appearance: /
• Density: 1.309g/cm³
• Vapor Pressure: 4.38E-05mmHg at 25°C
• Refractive Index: 1.54
• PKA: 14.62±0.46(Predicted)
• CAS DataBase Reference: 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE(42498-38-4)
• EPA Substance Registry System: 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE(42498-38-4)

Safety Data

• Hazard Codes: Xi
• Statements: 52
• Hazardous Substances Data: 42498-38-4(Hazardous Substances Data)

Usage

General Description

4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE, also known as bromocamphorquinone, is a chemical compound used in the production of photopolymerizable dental materials. It is a photosensitive compound that can initiate the polymerization process in dental restorative materials, such as composites and adhesive resins. 4-BROMO-N-(1,1-DIMETHYLETHYL)BENZAMIDE is a white to off-white powder with a molecular formula of C11H14BrNO and a molecular weight of 261.14 g/mol. It is important to handle and store this chemical with care, as it can be harmful if ingested or inhaled, and could cause skin and eye irritation upon contact.

InChI:InChI=1/C11H14BrNO/c1-11(2,3)13-10(14)8-4-6-9(12)7-5-8/h4-7H,1-3H3,(H,13,14)

Upstream product

• 75-64-9 tert-butylamine 
• 586-75-4 4-chlorobenzoyl chloride 
• 586-76-5 4-Bromobenzoic acid 
• 540-88-5 acetic acid tert-butyl ester 
• 623-00-7 4-bromobenzenecarbonitrile 
• 119072-55-8 tert-butylisonitrile 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 106-40-1 4-bromo-aniline 
• 1122-91-4 4-bromo-benzaldehyde 
• 106-38-7 para-bromotoluene 
• 201230-82-2 carbon monoxide 
• 589-87-7 1,4-bromoiodobenzene 
• 75-65-0 tert-butyl alcohol 
• 1712-82-9 p-bromodibenzoyl peroxide 

Downstream Products

• 102676-62-0 4-<3-<4-<(tert-butylamino)carbonyl>phenyl>-3-hydroxyprop-1-yl>-1-(triphenylmethyl)-1H-imidazole 
• 288093-13-0 N-(1,1-dimethylethyl)-4-(3-pyridyl)benzamide 
• 147223-89-0 1-benzyl-5-[4-(4-fluorophenyl)-1-hydroxy-1-(4-tert-butylaminocarbonylphenyl)butyl]-1H-imidazole 
• 698-67-9 p-bromobenzamide 
• 288093-19-6 N-tert-butyl-4-(1-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-benzamide 
• 288093-16-3 N-tert-butyl-4-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-benzamide 
• 102676-64-2 5-<4-<(tert-butylamino)carbonyl>phenyl>-6,7-dihydro-5H-pyrrolo<1,2-c>imidazole 
• 102676-65-3 5-(4-cyanophenyl)-6,7-dihydro-5H-pyrrolo<1,2-c>imidazole hydrochloride 
• 102676-63-1 4-<3-<4-<(tert-butylamino)carbonyl>phenyl>-3-chloroprop-1-yl>-1-(triphenylmethyl)-1H-imidazole 
• 112809-59-3 (4-chlorophenyl)-(4'-N-tert-butylcarbamoylphenyl)methanol 
• 147223-85-6 1-benzyl-5-[1-hydroxy-4-phenyl-1-(4-tert-butylaminocarbonylphenyl)butyl]-1H-imidazole 
• 586-76-5 4-Bromobenzoic acid 
• 1333434-97-1 4-(benzo[b]thiophen-3-yl)-N-(tert-butyl)benzamide 
• 1425194-11-1 N-tert-butyl-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)benzamide 

Relevant articles and documents

Electrochemical Benzylic C-H Functionalization with Isocyanides

We report the challenging direct carbamoylation or cyanation of benzylic C(sp3)-H bonds with an isocyanide via an electrochemical process giving rise to structures that are encountered in several biologically relevant compounds and drugs. This transformation proceeds under mild conditions without the need for any external oxidant and avoids the necessity to start from a prefunctionalized benzylic substrate or the deployment of the cation pool method. The anodic oxidation of the benzylic position and the subsequent addition of the isocyanide lead to the formation of a C-C bond and to a nitrilium cation that hydrolyzes to yield α-Aryl acetamide derivatives, whereas the elimination of a t-butyl cation delivers α-Aryl acetonitrile derivatives.

CoFe2O4?SiO2-NH-βCD-BF3 as a supramolecular nanocomposite: Synthesis, characterization and catalytic activity

This manuscript describes synthesis of BF3-functionlized β-cylcodextrine grafted magnetic CoFe2O4 nanaoparticles as a hybrid magnetic nano-composite (CoFe2O4?SiO2-NH-βCD-BF3). The CoFe2O4?SiO2-NH-βCD-BF3 was fabricated by grafting of 6-O-toluenesulfonyl cyclodextrin (6-Ts-βCD) to 3-aminopropyl triethoxysilane coated magnetic CoFe2O4?SiO2 nanoparticles followed by combination with BF3. The CoFe2O4?SiO2-NH-βCD-BF3was characterized by FT-IR, TGA, VSM and SEM techniques. The feasibility of using CoFe2O4?SiO2-NH-βCD-BF3 as a magnetically recoverable catalyst was confirmed in the modified-Ritter reaction. The result showed that this novel nano-composite could serve as an efficient nanoreactor bearing super-acidic sites formed by immobilized BF3 and reuse at least for 6 times without loss in activity.

Ionic liquid catalyzed Ritter reaction/Pd-catalyzed directed Ortho-arylation; facile access to diverse libraries of biaryl-amides from Aryl-nitriles

Diverse libraries of biaryl-amides bearing N-t-butyl and N-adamantyl groups were synthesized in two steps by the Ritter reaction of aryl-nitriles, using tBuOH and AdaOH as carbocation precursors, and employing [BMIM(SO3H)][OTf] (neat or with [B