4254-29-9Relevant articles and documents
A Mass Spectral Investigation of Water and Acetic Acid Elimination From 1- and 2-Indan Derivatives
Groenewold, G. S.,Gross, M. L.,Zey, R.
, p. 416 - 423 (1982)
Water and acetic acid eliminations from 1- and 2-indan derivatives have been investigated.Deuterium labeling, high resolution peak matching and the metastable peak analysis capabilities of a high resolution triple analyzer (E B E) mass spectrometer were employed to examine the eliminations.These experiments showed that water was lost from 1-indanol via 1,2 and 1,3 processes.These results contrast with those obtained for 1-tetralol, which specifically eliminates water in a 1,4 process involving the benzylic hydrogens.Water elimination from 2-indanol is preceded by a slow hydroxyl-benzylic hydrogen exchange and proceeds specifically 1,2.Water losses from both 1- and 2-indanol are characterized by large kinetic energy releases.Acetic acid elimination is shown to occur specifically 1,3 from 1-acetoxyindan and 1,2 from 2-acetoxyindan.
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Mizuno,K. et al.
, p. 1027 - 1030 (1977)
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Efficient Transfer Hydrogenation of Ketones using Methanol as Liquid Organic Hydrogen Carrier
Garg, Nidhi,Paira, Soumen,Sundararaju, Basker
, p. 3472 - 3476 (2020/05/29)
Herein, we demonstrate an efficient protocol for transfer hydrogenation of ketones using methanol as practical and useful liquid organic hydrogen carrier (LOHC) under Ir(III) catalysis. Various ketones, including electron-rich/electron-poor aromatic ketones, heteroaromatic and aliphatic ketones, have been efficiently reduced into their corresponding alcohols. Chemoselective reduction of ketones was established in the presence of various other reducible functional groups under mild conditions.
Direct Photorelease of Alcohols from Boron-Alkylated BODIPY Photocages
Fischer, Logan J.,Gehrmann, Elizabeth J.,Peterson, Julie A.,Shrestha, Pradeep,Smith, Emily A.,Wijesooriya, Chamari S.,Winter, Arthur H.,Yuan, Ding
supporting information, p. 5712 - 5717 (2020/05/19)
BODIPY photocages allow the release of substrates using visible light irradiation. They have the drawback of requiring reasonably good leaving groups for photorelease. Photorelease of alcohols is often accomplished by attachment with carbonate linkages, which upon photorelease liberate CO2 and generate the alcohol. Here, we show that boron-alkylated BODIPY photocages are capable of directly photoreleasing both aliphatic alcohols and phenols upon irradiation via photocleavage of ether linkages. Direct photorelease of a hydroxycoumarin dye was demonstrated in living HeLa cells.
Method for carrying out reduction on aldehyde and ketone to obtain alcohol
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Paragraph 0019; 0020; 0042; 0043, (2019/03/30)
The invention discloses a method for carrying out reduction on aldehyde and ketone to obtain alcohol. Tri-(pentafluorobenzene-base) borane is used as a catalyst, and hydrogen silane is used as a reducing agent. The method includes adding water into reaction systems and carrying out reduction on the aldehyde or the ketone under the normal-temperature condition to obtain the corresponding alcohol. Compared with the prior art, the method has the advantages that reaction can be quickly carried out under the normal-temperature and normal-pressure conditions, the reaction conditions are mild, the method is high in reaction efficiency, and the yield is 95%-100% as shown by 1H NMR (1H nuclear magnetic resonance) detection; the water can be used as a solvent used in the reaction, and accordingly the method is low in cost and little in pollution; the catalyst and the reducing agent do not contain heavy metal, and accordingly the problem of heavy metal pollution and the like can be solved by theaid of the method.
