42542-99-4

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-phenyl-
• CAS NO: 42542-99-4
• Molecular Formula: C12H12N2O2
• Molecular Weight: 216.239
• Mol File: 42542-99-4.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-phenyl-(42542-99-4)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-phenyl-(42542-99-4)

Safety Data

• Hazardous Substances Data: 42542-99-4(Hazardous Substances Data)

Upstream product

• 13345-09-0 6-phenyluracil 
• 77-78-1 dimethyl sulfate 
• 7033-39-8 5-bromo-1,3-dimethyluracil 
• 71-43-2 benzene 
• 6972-27-6 1,3-Dimethyl-6-chlorouracil 
• 33227-70-2 1,3-dimethyl-6-phenyl-1H-pyrimidine-2,4-dithione 
• 21428-19-3 N¹,N³-dimethyl-6-iodouracil 
• 98-86-2 acetophenone 
• 36822-11-4 6-phenyl-2-thiouracil 
• 874-14-6 1,3-dimethyluracil 
• 591-50-4 iodobenzene 
• 696-62-8 para-iodoanisole 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 960-16-7 tributylphenylstannane 

Downstream Products

• 1381948-80-6 C₁₂H₁₂Cl₂N₂O₃ 
• 1381948-78-2 5-chloro-1,3-dimethyl-6-phenyluracil 

Relevant articles and documents

Acid-catalyzed photoreaction of 6-chloro-1,3-dimethyluracil in frozen benzene: formation of novel cycloadducts, tetrahydropentaleno[1,2-e]pyrimidine-2,4-dione derivatives

Contrasting to the photoreaction of 6-chloro-1,3-dimethyluracil in benzene at ambient temperature in the presence of trifluoroacetic acid, whereby 1,3-dimethylcyclooctapyrimidine was produced as a sole cycloadduct, the similar photoreaction in frozen benzene at -15 ～ -20°C proceeded quite differently to give three novel photocycloadducts, 7-chloro-1,3-dimethyl-4b,5,7a,8-tetrahydropentaleno[1,2-e]pyrimidine-2,4-dione, 5-chloro-1,3-dimethyl-4b,7,7a,8-tetrahydropentaleno[1,2-e]pyrimidine-2,4-dione, ando-chloro-10,12-diazapentacyclo[6.4.0.01,3.02,5.0 4,8]-dodecane-9,11-dione.

Synthesis of 2-Arylpyridopyrimidinones, 6-Aryluracils, and Tri- and Tetrasubstituted Conjugated Alkenes via Pd-Catalyzed Enolic C-O Bond Activation-Arylation

A new and efficient approach for the synthesis of biologically important 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones and 6-aryluracils via previously unknown Pd-catalyzed enolic C-OH activation-arylation of pyridopyrimidin-2,4-diones and barbituric acids, res

Regioselective arylation of uracil and 4-pyridone derivatives via copper(I) bromide mediated C-H bond activation

A facile and effective synthesis of 6-aryluracil derivatives was accomplished by the direct C-H bond activation for arylation. A series of 6-aryl-1,3-dimethyluracils were synthesized from the reaction of 1,3-dimethyluracil with various phenyl iodides in DMF, in the presence of copper(I) bromide as the catalyst and lithium tert-butoxide as the base. This methodology is applicable to a variety of 5-substituted uracils as well as 4-pyridone to provide direct accesses to versatile uracil and 4-pyridone derivatives.