42545-43-7

Basic information

• Product Name: 2-(4-METHOXYPHENYL)THIOPHENE
• Synonyms: 2-(4-METHOXYPHENYL)THIOPHENE;AKOS BAR-0352;2-(4-METHOXYPHENYL)THIOPHENE,95%;2-p-Anisylthiophene
• CAS NO: 42545-43-7
• Molecular Formula: C₁₁H₁₀OS
• Molecular Weight: 190.26
• Mol File: 42545-43-7.mol
• Article Data: 161

Chemical Properties

• Boiling Point: 296.4 °C at 760 mmHg
• Flash Point: 133.1 °C
• Appearance: /
• Density: 1.131 g/cm³
• Vapor Pressure: 0.00254mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2-(4-METHOXYPHENYL)THIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENYL)THIOPHENE(42545-43-7)
• EPA Substance Registry System: 2-(4-METHOXYPHENYL)THIOPHENE(42545-43-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 42545-43-7(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxyphenyl)thiophene is a chemical compound that belongs to the class of thienyl compounds. It is characterized by a thiophene ring with a methoxy group attached to the phenyl group at the 2-position. This chemical has potential applications in the field of organic electronics and materials science due to its unique electronic and optical properties. It can be used as a building block in the synthesis of various organic compounds such as polymers, dyes, and pharmaceuticals. Additionally, 2-(4-Methoxyphenyl)thiophene has the potential to exhibit interesting biological activities, making it a subject of interest in medicinal chemistry research.

InChI:InChI=1/C11H10OS/c1-12-10-6-4-9(5-7-10)11-3-2-8-13-11/h2-8H,1H3

Upstream product

• 188290-36-0 thiophene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 696-62-8 para-iodoanisole 
• 81745-84-8 2-thienylzinc chloride 
• 96-43-5 2-thienyl chloride 
• 100-66-3 methoxybenzene 
• 1003-09-4 2-bromothiophene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 54663-78-4 tributyl(thien-2-yl)stannane 
• 18649-43-9 4-methoxyphenyllead(IV) triacetate 
• 733-53-9 p-methoxyphenyl(phenyl)iodonium tetrafluoroborate 
• 53034-24-5 2-thienyllead(IV) triacetate 
• 2665-61-4 (p-methoxyphenyl)(phenyl)iodonium bromide 
• 115298-63-0 phenyl(4-methoxyphenyl)iodonium triflate 

Downstream Products

• 29886-65-5 4-thiophen-2-yl-phenol 
• 83495-25-4 5,5'-Bis-(4-methoxy-phenyl)-[2,3']bithiophenyl 
• 38401-67-1 2-formyl-5-(4-methoxyphenyl)thiophene 
• 166964-20-1 5-(4-Methoxyphenyl)-2-thiophenesulfonyl chloride 
• 185993-18-4 3-(4-n0decylphenyl)thiophene 
• 185993-19-5 5-(4-n-decyloxyphenyl)thiophene-2-carboxylic acid 
• 130841-02-0 2-dicyanovinyl-5-(4-methoxyphenyl)thiophene 
• 1160457-06-6 C₁₈H₂₀O₃S 
• 1041011-51-1 butyl (E)-3-[5-(4-methoxyphenyl)-2-thienyl]-2-propenoate 
• 1257985-12-8 triisopropyl((5-(4-methoxyphenyl)thiophen-2-yl)ethynyl)silane 
• 1255940-10-3 (3-methoxy-4-methylphenyl)[5-(4-methoxyphenyl)-2-thienyl]methanone 
• 1255940-11-4 (4-fluoro-3-methoxyphenyl)[5-(4-methoxyphenyl)-2-thienyl]methanone 
• 1360187-08-1 2-(4-methoxyphenyl)-5-(4-trifluoromethylphenyl)thiophene 

Relevant articles and documents

Organozinc-mediated direct cross-coupling under microwave irradiation

We report a direct cross-coupling reaction between (het)aryl pivalates/tosylates and di(het)arylzinc species in 2-methyltetrahydrofuran/N-methyl pyrrolidone (1:1), which occurs via C–O bond cleavage under microwave irradiation. The reaction takes place smoothly in short reaction times without the addition of any catalyst or ligand. The reaction is suitable for a broad scope of substrates and exhibits good functional group compatibility, utilizes a simple work-up procedure, and gives the desired products in high purity.

Pyrazole-Mediated C-H Functionalization of Arene and Heteroarenes for Aryl-(Hetero)aryl Cross-Coupling Reactions

Herein we introduce a transition-metal-free protocol that involves a commercially available, inexpensive pyrazole molecule to conduct C-C cross-coupling reactions at room temperature via a radical pathway. Using this method, an aryldiazonium salt has been coupled to a wide range of arenes and heteroarenes including benzene, mesitylene, thiophene, furan, benzoxazole to result the corresponding biaryl products. The full reaction mechanism is elucidated along with the crystallographic probation of an active initiator species. A potassium-stabilized deprotonated pyrazole steers single-electron transfer to the substrate and behaves as an initiator for the reaction.

Pd Nanoparticles Embedded Into MOF-808: Synthesis, Structural Characteristics, and Catalyst Properties for the Suzuki–Miyaura Coupling Reaction

Abstract: A heterogeneous single-site catalyst Pd@MOF-808 was successfully synthesized by water-based, green synthesis procedure. The catalytic experiments exhibited the Pd@MOF-808 promoted efficiently the Suzuki–Miyaura coupling reaction without the assistance of organic phosphine ligands at atmospheric pressure conditions. The catalyst also could be applied in the gram-scale synthesis of industrially anti-inflanmatory analgestic Fenbufen. Graphic Abstract: [Figure not available: see fulltext.]