4258-83-7 Usage
Description
(16α)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione is a light yellow solid with a complex chemical structure, characterized by its unique arrangement of carbon atoms and functional groups. It is a derivative of pregna-1,4,9(11)-triene, featuring a 16-methyl group and an acetyloxy group at the 21-position. (16α)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione is known for its potential applications in the pharmaceutical industry, particularly in the development of amino steroids for the treatment of neurological disorders.
Uses
Used in Pharmaceutical Industry:
(16α)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione is used as a key intermediate compound in the synthesis of amino steroids. These amino steroids are valuable for their therapeutic potential in treating various neurological disorders, such as epilepsy, multiple sclerosis, and neurodegenerative diseases. (16α)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione's unique structure allows for the development of novel drugs with improved efficacy and reduced side effects.
Chemical Properties:
(16α)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione is a light yellow solid, which indicates its stability and suitability for use in chemical reactions and pharmaceutical formulations. Its solid-state form facilitates handling, storage, and transportation, making it a practical choice for industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4258-83-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,5 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4258-83:
(6*4)+(5*2)+(4*5)+(3*8)+(2*8)+(1*3)=97
97 % 10 = 7
So 4258-83-7 is a valid CAS Registry Number.
4258-83-7Relevant articles and documents
Expedient synthesis of 17α,21-dihydroxy-9β,11β-epoxy- 16αmethylpregna- 1,4-diene-3,20-dione 21-acetate from prednisolone utilising a novel Mattox rearrangement
Hulcoop, David G.,Shapland, Peter D.P.
, p. 1281 - 1287 (2013/11/06)
A six step transformation of prednisolone to 17a,21-dihydroxy-9b,11b-epoxy- 16a-amethylpregna-1,4- diene-3,20-dione 21-acetate has been achieved in 13% unoptimised yield. Novel conditions for effecting a Mattox rearrangement and double dehydration of prednisolone were identified. Enhanced knowledge on the oxidation of silyl D19,20-enol ethers and structural factors that impact the success of the oxidation are also presented.
