426823-57-6

Basic information

• Product Name: 3-bromo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one
• Synonyms: 3-bromo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one
• CAS NO: 426823-57-6
• Molecular Weight: 347.255
• Mol File: 426823-57-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one(426823-57-6)
• EPA Substance Registry System: 3-bromo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one(426823-57-6)

Safety Data

• Hazardous Substances Data: 426823-57-6(Hazardous Substances Data)

Upstream product

• 13466-43-8 3-bromopyridin-2(1H)-one 
• 5407-61-4 1-phenyl-2-(pyrrolidin-1-yl)ethanol 
• 142-08-5 2-hydroxypyridin 
• 70-11-1 α-bromoacetophenone 
• 2218-15-7 1-phenyl-2-(pyrrolidin-1-yl)ethanone 
• 96-09-3 styrene oxide 
• 51166-57-5 1-(2-chloro-2-phenylethyl)pyrrolidine 

Relevant articles and documents

Synthesis and Biological activity of kappa opioid receptor agonists. Part 2: Preparation of 3-aryl-2-pyridone analogues generated by solution- and solid-phase parallel synthesis methods

New analogues of the previously described 3-aryl pyridone KOR agonists have been synthesised by parallel synthetic methods, both in solution- and with solid-phase chemistry, making use of the well known and versatile Mitsunobu, Suzuki and Buchwald reactions. Opioid receptor binding data for the compounds produced is reported.