426825-75-4

Basic information

• Product Name: 6-IODOIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 6-IODOIMIDAZO[1,2-A]PYRIDINE;6-iodoH-imidazo[1,2-a]pyridine
• CAS NO: 426825-75-4
• Molecular Formula: C₇H₅IN₂
• Molecular Weight: 244.03
• Product Categories: Heterocycle-Pyridine series
• Mol File: 426825-75-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 130-131°C
• Appearance: /
• Density: 2.015 g/cm³
• Refractive Index: 1.75
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.27±0.50(Predicted)
• CAS DataBase Reference: 6-IODOIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-IODOIMIDAZO[1,2-A]PYRIDINE(426825-75-4)
• EPA Substance Registry System: 6-IODOIMIDAZO[1,2-A]PYRIDINE(426825-75-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 426825-75-4(Hazardous Substances Data)

Usage

General Description

6-Iodoimidazo[1,2-a]pyridine is a chemical compound that belongs to the class of organic compounds known as imidazopyridines. These are organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. 6-Iodoimidazo[1,2-a]pyridine is generally used in preparational chemistry as a chemical intermediate. It is characterized by the substitution of the iodo group at the sixth position of the imidazo[1,2-a]pyridine system. Specific details such as its physical and chemical properties, toxicity levels, and reactivity traits can vary depending on its exact molecular structure.

InChI:InChI=1/C7H5IN2/c8-6-1-2-7-9-3-4-10(7)5-6/h1-5H

Upstream product

• 107-20-0 2-chloroethanal 
• 88511-25-5 2-amino-6-iodopyridine 
• 20511-12-0 2-amino-5-iodopyridine 
• 504-29-0 2-aminopyridine 

Downstream Products

• 328062-45-9 6-phenylimidazo[1,2-a]pyridine 
• 690258-23-2 6-iodo-3-nitroimidazo[1,2-a]pyridine 
• 1146615-52-2 3-bromo-6-iodoimidazo[1,2-a]pyridine 
• 958641-89-9 2-[3'-(2-t-butyldiphenylsiloxyethoxy)phenyl]-6-iodoimidazo[1,2-a]pyridine 
• 1205744-30-4 6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-amine 
• 1205744-31-5 4-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}aniline 
• 1205744-32-6 N-(4-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-phenyl)acetamide 
• 1205744-33-7 3-bromo-6-(4-fluorophenyl)imidazo[1,2-a]pyridine 
• 1205744-35-9 N-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)cyclopropanecarboxamide 
• 1205744-36-0 N-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)acetamide 
• 1205744-37-1 1-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)-3-(2-methoxyethyl)urea 
• 1205744-38-2 phenyl (6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)carbamate 
• 1205744-34-8 6-(4-fluorophenyl)imidazo[1,2-a]pyridine 
• 955376-51-9 6-methoxyimidazo[1,2-a]pyridine 

Relevant articles and documents

BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

The present invention relates to compounds of general formula (I), wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

NOVEL FUSED IMIDAZOLE DERIVATIVE

The present invention relates to a compound represented by the Formula [I]: Wherein: the A ring is a 5-membered aromatic heterocyclic group containing at least one hetero atom selected from a nitrogen atom, and the like; A1 and A2, are each a nitrogen atom, and the like; X2, X3, X4, and X5 are all carbon atoms, or alternatively any one of X2, X3, X4, and X5 is a nitrogen atom and the rest are all carbon atoms; R1 is a hydrogen atom, or the like; R2, R3, R4, and R5, are each a hydrogen atom, or the like; R6 and R6', are each a hydrogen atom, and the like; R7 is an aryl group and the like; and R8 is an amino group or a hydroxy group, or a pharmaceutically acceptable salt or ester thereof.

NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS

The current invention relates to compounds of the formula:(Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.