428861-42-1

Basic information

• Product Name: 1H-Indole-2-carboxylicacid,2,3-dihydro-6-nitro-(9CI)
• Synonyms: 1H-Indole-2-carboxylicacid,2,3-dihydro-6-nitro-(9CI);6-nitroindoline-2-carboxylic acid;2,3-Dihydro-6-nitro-1H-indole-2-carboxylic acid;6-nitro-2,3-dihydro-1H-indole-2-carboxylic acid
• CAS NO: 428861-42-1
• Molecular Formula: C9H8N2O4
• Molecular Weight: 208.17082
• Product Categories: AMINOACID
• Mol File: 428861-42-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.501
• CAS DataBase Reference: 1H-Indole-2-carboxylicacid,2,3-dihydro-6-nitro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylicacid,2,3-dihydro-6-nitro-(9CI)(428861-42-1)
• EPA Substance Registry System: 1H-Indole-2-carboxylicacid,2,3-dihydro-6-nitro-(9CI)(428861-42-1)

Safety Data

• Hazardous Substances Data: 428861-42-1(Hazardous Substances Data)

Usage

Description

1H-Indole-2-carboxylic acid, 2,3-dihydro-6-nitro-(9CI) is a chemical compound with the molecular formula C10H9NO4. It is a derivative of indole with a carboxylic acid and a nitro group on the 2 and 6 positions, respectively.

Uses

Used in Pharmaceutical Synthesis:
1H-Indole-2-carboxylic acid, 2,3-dihydro-6-nitro-(9CI) is used as an intermediate in the synthesis of various pharmaceuticals and chemical products. Its unique structure and functional groups make it a valuable building block for the development of new drugs and compounds.
Used in Biological Research:
1H-Indole-2-carboxylic acid, 2,3-dihydro-6-nitro-(9CI) is used as a research tool in biological studies. Its potential antimicrobial and anti-inflammatory properties are being investigated, which could lead to the discovery of new therapeutic agents.
However, it is important to note that the specific applications and uses of 1H-Indole-2-carboxylic acid, 2,3-dihydro-6-nitro-(9CI) are still under investigation, and further research is needed to fully understand its potential benefits and risks.

Upstream product

• 16851-56-2 indolin-2-yl carboxylic acid 

Downstream Products

• 136818-66-1 6-Nitro-1H-indole-2-carboxylic acid methyl ester 
• 167027-30-7 methyl 6-amino-1H-indole-2-carboxylate 

Relevant articles and documents

5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES

The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, the treatment of HIV, autoimmune diseases, infections, atherosclerosis, and ischemia–reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE

Disclosed is a compound represented by the formula (I): wherein R1 and R2 independently represent a hydrogen atom, a lower alkyl group or the like; X1, X2 and X3 independently represent a methine group or a nitrogen atom; Y1 and Y3 independently represent a single bond, -O- or the like; Y2 represents a lower alkylene group or the like; W1 to W4 independently represent a single bond, a methlene group or the like; L represents a single bond, a methylene group or the like; Z1 and Z2 independently represent a single bond, a C1-4 alkylene group or the like; Ar1 represents an aromatic carbocyclic ring or the like; and Ar2 represents a bicyclic aromatic carbocyclic ring or the like. The compound is useful as a pharmaceutical for a central disease, a cardiovascular disease or a metabolic disease.