43020-09-3

Basic information

• Product Name: 1-(5-methyl-2-phenylfuran-3-yl)ethan-1-one
• Synonyms: 1-(5-methyl-2-phenylfuran-3-yl)ethan-1-one
• CAS NO: 43020-09-3
• Molecular Weight: 200.237
• Mol File: 43020-09-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1-(5-methyl-2-phenylfuran-3-yl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-methyl-2-phenylfuran-3-yl)ethan-1-one(43020-09-3)
• EPA Substance Registry System: 1-(5-methyl-2-phenylfuran-3-yl)ethan-1-one(43020-09-3)

Safety Data

• Hazardous Substances Data: 43020-09-3(Hazardous Substances Data)

Upstream product

• 93-91-4 1-phenylbutan-1,3-dione 
• 70244-88-1 1-phenyl-2-(prop-2-ynyl)butane-1,3-dione 
• 81396-46-5 3-benzoylhexane-2,5-dione 
• 146896-35-7 3-acetyl-4,5-dihydro-2-phenyl-5-<(phenylseleno)methyl>furan 
• 10225-38-4 1-phenyl-2-(2-propenyl)-1,3-butanedione 
• 106-96-7 propargyl bromide 
• 105-53-3 diethyl malonate 
• 183210-32-4 5-methyl-2-phenylfuran-3-carbonyl chloride 
• 146896-45-9 3-acetyl-4,5-dihydro-5-methylene-2-phenylfuran 

Downstream Products

• 90043-64-4 1-((2R,3R)-3-Acetyl-2-benzoyl-oxiranyl)-ethanone 
• 90043-64-4 1-((2R,3S)-3-Acetyl-2-benzoyl-oxiranyl)-ethanone 
• 60975-12-4 (Z)-3-Benzoyl-hex-3-ene-2,5-dione 
• 183210-43-7 3-acetyl-5-(bromomethyl)-2-phenylfuran 
• 90043-57-5 5-Acetyl-1-methyl-4-phenyl-2,3,7-trioxabicyclo<2.2.1>hept-5-ene 

Relevant articles and documents

Synthesis of 3-Carbonyl Trisubstituted Furans via Pd-Catalyzed Aerobic Cycloisomerization Reaction: Development and Mechanistic Studies

Herein, we report the synthesis of 3-carbonyl-trisubstituted furans via Pd-catalyzed oxidative cycloisomerization reactions of 2-alkenyl-1,3-dicarbonyl scaffolds, using molecular oxygen as the sole oxidant to regenerate active palladium catalytic species, featuring good functional tolerance and mild reaction conditions. Deep investigation of intermediates and transition states of the reaction mechanism were conducted via experimental and DFT studies, providing a detailed mechanistical profile. The new developed methodology presents a greener alternative to Wacker-type cycloisomerizations and avoids the use of stoichiometric amounts of oxidants and strong acid additives.

Method for preparing poly-substituted furan compound by condensing tricarbonyl compound under effect of titanium tetrachloride

The invention provides a method for preparing a poly-substituted furan compound by condensing a tricarbonyl compound under an effect of titanium tetrachloride. The method comprises the following steps: by taking methylene dichloride or methylbenzene as a solvent, causing the tricarbonyl compound react with titanium tetrachloride while stirring under inert gas shielding, ending the reaction and then separating, thereby acquiring the poly-substituted furan compound. The compounding method provided by the invention has the characteristics of easily acquired raw materials, low cost, mild reaction condition, simple and easily controlled operation, less side reaction, simple post-processing, higher product yield, capability of greatly saving production cost, higher economic benefit and suitability for industrial mass production.

Polymer-supported selenium-induced electrophilic cyclization: Solid-phase synthesis of poly-substituted dihydrofurans and tetrahydrofurans

Poly-substituted dihydrofurans and tetrahydrofurans have been synthesized through polymer-supported selenium-induced intramolecular electrophilic cyclization, followed by selenoxide syn-elimination or novel nucleophilic substitution cleavage of selenium resin with good yields and purities. Graphical Abstract