4328-13-6 Usage
Description
TETRA-N-HEXYLAMMONIUM BROMIDE is a white to faintly yellow powder that serves as an ion-pairing reagent used in various applications, particularly in the field of chemistry and pharmaceuticals. It is known for its ability to act as a hydrogen bond acceptor and as a phase transfer salt, making it a versatile compound for different industries.
Uses
Used in Chemical Industry:
TETRA-N-HEXYLAMMONIUM BROMIDE is used as a hydrogen bond acceptor for the preparation of deep eutectic solvents, which are utilized in the desulfurization and denitrogenation processes from n-heptane. This application helps in reducing harmful emissions and improving the quality of the final product.
Used in Environmental Science:
In the field of environmental science, TETRA-N-HEXYLAMMONIUM BROMIDE is used to produce an aqueous biphasic system for the preconcentration of heavy metal ions. This system aids in the efficient removal and recovery of heavy metals from various waste streams, contributing to a cleaner environment.
Used in Analytical Chemistry:
TETRA-N-HEXYLAMMONIUM BROMIDE is employed as a phase transfer salt in the fabrication of optical chemical gas sensors. These sensors are crucial in detecting and monitoring the presence of specific gases in various environments, ensuring safety and compliance with environmental regulations.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TETRA-N-HEXYLAMMONIUM BROMIDE is used as an ion-pairing reagent in reversed phase high-performance liquid chromatography (HPLC) columns. The purity and effectiveness of this compound make it an essential component in the successful analysis of anionic and cationic substances, contributing to the development and quality control of various drugs and medications.
Purification Methods
Wash the bromide with ether, and dry it in a vacuum at room temperature for 3 days.
Check Digit Verification of cas no
The CAS Registry Mumber 4328-13-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,2 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4328-13:
(6*4)+(5*3)+(4*2)+(3*8)+(2*1)+(1*3)=76
76 % 10 = 6
So 4328-13-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H52N.BrH/c1-5-9-13-17-21-25(22-18-14-10-6-2,23-19-15-11-7-3)24-20-16-12-8-4;/h5-24H2,1-4H3;1H/q+1;/p-1
4328-13-6Relevant articles and documents
Effects of charge separation, effective concentration, and aggregate formation on the phase transfer catalyzed alkylation of phenol
Denmark, Scott E.,Weintraub, Robert C.,Gould, Nathan D.
supporting information; experimental part, p. 13415 - 13429 (2012/09/25)
The factors that influence the rate of alkylation of phenol under phase transfer catalysis (PTC) have been investigated in detail. Six linear, symmetrical tetraalkylammonium cations, Me4N+, Et 4N+, (n-Pr)4N+, (n-Bu) 4N+, (n-Hex)4N+, and (n-Oct) 4N+, were examined to compare the effects of cationic radius and lipophilicity on the rate of alkylation. Tetraalkylammonium phenoxide·phenol salts were prepared, and their intrinsic reactivity was determined from initial alkylation rates with n-butyl bromide in homogeneous solution. The catalytic activity of the same tetraalkylammonium phenoxides was determined under PTC conditions (under an extraction mechanism) employing quaternary ammonium bromide catalysts. In homogeneous solution the range in reactivity was small (6.8-fold) for Me4N+ to (n-Oct) 4N+. In contrast, under PTC conditions a larger range in reactivity was observed (663-fold). The effective concentration of the tetraalkylammonium phenoxides in the organic phase was identified as the primary factor influencing catalyst activity. Additionally, titration of active phenoxide in the organic phase confirmed the presence of both phenol and potassium phenoxide aggregates with (n-Bu)4N+, (n-Hex)4N+, and (n-Oct)4N+, each with a unique aggregate stoichiometry. The aggregate stoichiometry did not affect the PTC initial alkylation rates.
