4352-53-8

Basic information

• Product Name: Cyclohexanenonanoic acid
• CAS NO: 4352-53-8
• Molecular Formula: C15H28O2
• Molecular Weight: 240.386
• Mol File: 4352-53-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanenonanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanenonanoic acid(4352-53-8)
• EPA Substance Registry System: Cyclohexanenonanoic acid(4352-53-8)

Safety Data

• Hazardous Substances Data: 4352-53-8(Hazardous Substances Data)

Upstream product

• 16269-06-0 9-phenylnonanoic acid 
• 50530-09-1 9-bromononanoic acid sodium salt 
• 931-50-0 cyclohexylmagnesium bromide 
• 861618-17-9 9-cyclohexyl-9-hydroxy-nonanoic acid methyl ester 
• 7789-60-8 phosphorus tribromide 
• 4354-52-3 7-cyclohexylheptanoic acid 
• 105-53-3 diethyl malonate 
• 645-45-4 hydrocinnamic acid chloride 
• 1129-66-4 5-Cyclohexyl-1-pentanol 
• 5962-88-9 5-cyclohexylvaleric acid 
• 2270-20-4 5-Phenylpentanoic acid 
• 16275-33-5 2-(3-phenylpropanoyl)cyclohexanone 
• 54089-03-1 1-bromo-5-cyclohexylpentane 

Downstream Products

• 1453071-43-6 3-(9-cyclohexyl-N-hydroxynonanamido)propanoic acid 
• 1454255-87-8 C₂₂H₄₁NO₄ 
• 1454255-81-2 C₂₉H₄₇NO₄ 
• 14561-42-3 2-hydroxy-3-(8-cyclohexyloctyl)-1,4-naphthoquinone 

Relevant articles and documents

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity

Histone Nε-methyl lysine demethylases KDM2/7 have been identified as potential targets for cancer therapies. On the basis of the crystal structure of KDM7B, we designed and prepared a series of hydroxamate analogues bearing an alkyl chain. Enzyme assays revealed that compound 9 potently inhibits KDM2A, KDM7A, and KDM7B, with IC50s of 6.8, 0.2, and 1.2 μM, respectively. While inhibitors of KDM4s did not show any effect on cancer cells tested, the KDM2/7-subfamily inhibitor 9 exerted antiproliferative activity, indicating the potential for KDM2/7 inhibitors as anticancer agents.