4372-32-1Relevant articles and documents
Mixed-ligand manganese(II)-phenolate complexes: Study of DNA cleavage, cytotoxic activity, and induction of apoptosis
Gao, En-Jun,Zhang, Ying,Lin, Lin,Wang, Ren-Shu,Dai, Lei,Liang, Qi,Zhu, Ming-Chang,Wang, Mei-Lin,Liu, Lei,He, Wen-Xuan,Zhang, Yan-Jin
, p. 3992 - 4005 (2011)
Two manganese complexes, [Mn(L1)2(dibe) 2](L1) (1) and [Mn(L2)2(dibe) 2] (2) (where L1= 2,2'- bipyridine (bipy), L 2=1,10-phenanthroline (phen)), were synthesized by using a carboxylic acid ligand (dibe= 2,2-dibenzylmalonate acid). The two complexes were characterized using IR, elemental analysis, and X-ray crystallography. Fluorescence analysis indicates that the two complexes can bind to HeLa cell DNA (HC-DNA), and gel electrophoresis assay demonstrates the ability of the complexes to cleave the HC-DNA. The two complexes exhibit cytotoxic specificity and significant cancer cell inhibitory rate. Furthermore, apoptotic tests demonstrate that these two complexes have apoptotic effects on HeLa cells. 2011 Taylor & Francis.
Some unusual reactions of Meldrum's acid. Synthesis of cinnamic acids, coumarins and 2-benzyl-1-indanone
Mahulikar,Mane
, p. 12 - 14 (2007/10/03)
The use of Meldrum's acid (1) in the synthesis of the substituted cinnamic acid 3 and malonic acid 4, the coumarins 8 and 9, and of 2-benzyl-1-indanone (13), is reported. The structure of benzylidene benzalmalonate is corrected to 14.
Microwave assisted hydrolysis of Meldrum's acid derivatives and decarboxylation of derived malonic acids
Helavi,Solabannavar,Desai,Mane
, p. 174 - 175 (2007/10/03)
Microwave induced hydrolysis of alkyl Medrum's acids and decarboxylation of derived malonic acids using poly-4-vinylpyridine as a catalyst gives high yields of carboxylic acids in a short time.
