438249-54-8

Basic information

• Product Name: 4-(4-Chloro-2-methoxy-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine
• CAS NO: 438249-54-8
• Molecular Weight: 394.784
• Mol File: 438249-54-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Chloro-2-methoxy-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Chloro-2-methoxy-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine(438249-54-8)
• EPA Substance Registry System: 4-(4-Chloro-2-methoxy-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine(438249-54-8)

Safety Data

• Hazardous Substances Data: 438249-54-8(Hazardous Substances Data)

Upstream product

• 204394-69-4 4-chloro-2-(3-pyridyl)-6-(trifluoromethyl)pyrimidine 
• 6376-14-3 2-methoxy-5-methyl-4-chloroaniline 

Relevant articles and documents

Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 2-aryl-4-arylaminopyrimidine and analogs thereof, represented by the general Formula I: wherein A, Ar1, Ar2, R1 and R3 are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. The compounds of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.