439575-02-7 Usage
Description
N-(5-((5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide, also known as BMS 509744, is a potent and selective inhibitor of interleukin-2 inducible T cell kinase (ITK). It is a complex organic compound with a unique chemical structure that allows it to target and inhibit the activity of ITK, a protein involved in T cell activation and immune response.
Uses
Used in Pharmaceutical Industry:
BMS 509744 is used as an ITK inhibitor for the treatment of HIV infection. It has been shown to reduce HIV infection of primary CD4+ T cells in vitro, making it a promising candidate for the development of new antiretroviral therapies.
Used in Immunology Research:
BMS 509744 is also used as a research tool in immunology to study the role of ITK in T cell activation and immune response. By inhibiting ITK activity, researchers can gain insights into the molecular mechanisms underlying T cell function and the regulation of the immune system.
Check Digit Verification of cas no
The CAS Registry Mumber 439575-02-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,9,5,7 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 439575-02:
(8*4)+(7*3)+(6*9)+(5*5)+(4*7)+(3*5)+(2*0)+(1*2)=177
177 % 10 = 7
So 439575-02-7 is a valid CAS Registry Number.
439575-02-7Relevant articles and documents
Synthesis method for thiazole compound with tyrosine kinase inhibitory activity
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, (2016/11/17)
The invention relates to a synthesis method for a thiazole compound (I) with tyrosine kinase inhibitory activity. Compound (3) and compound (II) react under the effect of a condensing agent, and thereby the compound (I) is obtained. The synthesis method i
