441713-58-2

Basic information

• Product Name: 2-benzyloxy-3,4-difluoro-1-nitrobenzene
• Synonyms: 2-benzyloxy-3,4-difluoro-1-nitrobenzene
• CAS NO: 441713-58-2
• Molecular Weight: 265.216
• Mol File: 441713-58-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-benzyloxy-3,4-difluoro-1-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxy-3,4-difluoro-1-nitrobenzene(441713-58-2)
• EPA Substance Registry System: 2-benzyloxy-3,4-difluoro-1-nitrobenzene(441713-58-2)

Safety Data

• Hazardous Substances Data: 441713-58-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 82419-26-9 2,3-difluoro-6-nitrophenol 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1198054-23-7 dimethyl (3-benzyloxy-2-fluoro-4-nitrophenyl)malonate 
• 1191103-79-3 5-[3-(benzyloxy)-2-fluoro-4-nitrophenoxy]-2-(methylsulfonyl)pyridine 
• 441713-59-3 di-tert-butyl (3-benzyloxy-2-fluoro-4-nitrophenyl)malonate 
• 115551-33-2 2-hydroxy 3,4-difluoro aniline 
• 163733-99-1 4-amino-2,3-difluoro-phenol 

Relevant articles and documents

FUSED RING COMPOUNDS AND USE THEREOF

The present invention aims to provide a glucokinase activator useful as a pharmaceutical agent such as an agent for the prophylaxis or treatment of diabetes, obesity and the like. The present invention provides a glucokinase activator containing a compoun

NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3)

A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen or the like.]

VLA-4 INHIBITORS

The present invention relates to a compound represented by the following formula (I): (wherein, W represents WA-A1 -WB - (in which, WA is substituted or unsubstituted aryl, etc., A1 is -NR1-, single bond, -C(O)-, etc., and WB is substituted or unsubstituted arylene, etc.), R is single bond, -NH-, -OCH2-, alkenylene, etc., X is -C(O) -CH2-, etc., and M is, for example, the following formula: (in which, R11, R12 and R13 each independently represents hydrogen, hydroxyl, amino, halogen, etc., R14 is hydrogen or lower alkyl, Y represents -CH2-O-, etc., Z is substituted or unsubstituted arylene, etc., A2 is single bond, etc, and R10 is hydroxyl or lower alkoxy)), or salt thereof; and a medicament containing the same. This compound or salt thereof selectively inhibits binding of cell adhesion molecules to VAL-4 and exhibits high bioavailability so that it is useful as a preventive and/or remedy for inflammatory diseases, autoimmune diseases, metastasis, bronchial asthma, rhinostenosis, diabetes, and the like.