4426-47-5 Usage
Chemical Properties
white to faintly beige shinying platelets
Uses
Different sources of media describe the Uses of 4426-47-5 differently. You can refer to the following data:
1. n-Butylboronic acid can be used in suzuki reaction.
2. n-Butylboronic acid is a boronic acid derivative that can be used as a transport carriers in membrane-based sugar separations. n-Butylboronic acid is used as an analytical reagent in the determination of serum glucose.
3. 1-Butylboronic acid is used as a reagent for preparation of volatile derivatives of diols, e.g. carbohydrates, for GC and mass spectrometry and to prepare chiral oxazaborolidines. It is a precursor to unsymmetric borinic acids, which are inhibitors of serine proteases. Can be used as a transport carrier in membrane-based sugar separations and as an analytical reagent in the determination of serum glucose.
Purification Methods
Butylboronic acid (1-butanedihydroxyborane) [4426-47-5] M 101.9, m 90 -92o, 94 -96o, pKEst ~8.8.acuo. [Corey et al. J Am Chem Soc 116 3151 1994, Quallich et al. J Am Chem Soc 116 8515 1994, Seerden Tetrahedron Lett 35 4419 1994, Beilstein 4 IV 4383.]
Check Digit Verification of cas no
The CAS Registry Mumber 4426-47-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,2 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4426-47:
(6*4)+(5*4)+(4*2)+(3*6)+(2*4)+(1*7)=85
85 % 10 = 5
So 4426-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H11BO2/c1-2-3-4-5(6)7/h6-7H,2-4H2,1H3
4426-47-5Relevant articles and documents
Dworkin,Van Artsdalen
, p. 4316 (1954)
Mattraw, H. C.,Erickson, C. E.,Laubengayer, A. W.
, p. 4901 - 4904 (1956)
COMPOUNDS AND SYNTHETIC METHODS FOR THE PREPARATION OF RETINOID X RECEPTOR-SPECIFIC RETINOIDS
-
Paragraph 198; 199, (2019/06/05)
Provided herein are compounds useful for the preparation of compounds that have retinoid-like biological activity. Also provided herein are processes for the preparation of compounds that have retinoid-like biological activity.
Amino acid-promoted C-H alkylation with alkylboronic acids using a removable directing group
Zhang, Yanghui,Zhang, Yu,Jiang, Hang,Chen, Dushen
supporting information, p. 4585 - 4589 (2016/06/09)
Palladium-catalyzed C-H alkylation reaction with alkylboronic acids has successfully been developed using a removable pyridyldiisopropylsilyl directing group. The amino acid played a crucial role as a ligand in the reaction. The alkylation protocol is also applicable to the coupling of C(sp3)-H bonds with alkylboronic acids.
P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease
Priestley,De Lucca, Indawati,Ghavimi, Bahman,Erickson-Viitanen, Susan,Decicco, Carl P.
, p. 3199 - 3202 (2007/10/03)
A series of peptide boronic acids containing extended, hydrophobic P1 residues was prepared to probe the shallow, hydrophobic S1 region of HCV NS3 protease. The p-trifluoromethylphenethyl P1 substituent was identified as optimal with respect to inhibitor potency for NS3 and selectivity against elastase and chymotrypsin.