4430-47-1 Usage
Description
3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE is an organic compound characterized by the presence of a methylenedioxybenzyl group and an isothiocyanate functional group. It is known for its reactivity in various chemical reactions, particularly nucleophilic addition reactions, making it a versatile building block in the synthesis of different organic molecules.
Uses
Used in Chemical Synthesis:
3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE is used as an intermediate in the chemical synthesis of various organic compounds. Its unique structure allows it to participate in nucleophilic addition reactions, which are crucial for the formation of new chemical bonds and the creation of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE is used as a key intermediate in the synthesis of bioactive molecules with potential therapeutic applications. Its ability to undergo nucleophilic addition reactions enables the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE is also utilized in the agrochemical industry for the synthesis of compounds with pesticidal properties. Its reactivity in nucleophilic addition reactions allows for the creation of new molecules with enhanced insecticidal, herbicidal, or fungicidal activities.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE serves as an intermediate for the production of various colored compounds. Its unique structure contributes to the development of dyes and pigments with improved color intensity, stability, and application properties.
Overall, 3,4-(METHYLENEDIOXY)BENZYL ISOTHIOCYANATE is a valuable compound in various industries due to its reactivity and versatility in chemical synthesis, making it a crucial component in the development of new molecules with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4430-47-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,3 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4430-47:
(6*4)+(5*4)+(4*3)+(3*0)+(2*4)+(1*7)=71
71 % 10 = 1
So 4430-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO2S/c13-5-10-4-7-1-2-8-9(3-7)12-6-11-8/h1-3H,4,6H2
4430-47-1Relevant articles and documents
A novel one-pot synthesis of isothiocyanates and cyanamides from dithiocarbamate salts using environmentally benign reagent tetrapropylammonium tribromide
Kuotsu, Neivotsonuo Bernadette,Jamir, Latonglila,Phucho, Tovishe,Sinha, Upasana Bora
, p. 832 - 841 (2018/01/17)
A highly efficient and simple protocol for the synthesis of isothiocyanates and cyanamides from their respective amines in the presence of a mild, efficient, and non-toxic reagent tetrapropylammonium tribromide is described. High environmental acceptability of the reagents, cost effectiveness and high yields are the important attributes of this methodology.
Synthesis and structure-activity relationship of non-peptidic antagonists of neuropilin-1 receptor
Liu, Wang-Qing,Megale, Valentino,Borriello, Lucia,Leforban, Bertrand,Montes, Matthieu,Goldwaser, Elodie,Gresh, Nohad,Piquemal, Jean-Philip,Hadj-Slimane, Reda,Hermine, Olivier,Garbay, Christiane,Raynaud, Francoise,Lepelletier, Yves,Demange, Luc
, p. 4254 - 4259 (2014/09/29)
Neuropilins (NRPs) are VEGF-A165 co-receptors over-expressed in tumor cells, and considered as targets in angiogenic-related pathologies. We previously identified compound 1, the first non-peptidic antagonist of the VEGF-A165/NRP binding, which exhibits in vivo anti-angiogenic and anti-tumor activities. We report here the synthesis and biological evaluations of new antagonists structurally-related to compound 1. Among these molecules, 4a, 4c and 4d show cytotoxic effects on HUVEC and MDA-MB-31 cells, and antagonize VEGF-A165/NRP-1 binding. This study confirmed our key structure-activity relationships hypothesis and paved the way to compound 1 'hit to lead' optimization.
Environmentally benign one-pot synthesis of cyanamides from dithiocarbamates using I2 and H2O2
Jamir, Latonglila,Sinha, Upasana Bora,Nath, Jayashree,Patel, Bhisma K.
experimental part, p. 951 - 958 (2012/02/01)
An environmentally benign reaction is devised for the synthesis of cyanamides from dithiocarbamate salts using iodine and H2O 2. Taylor & Francis Group, LLC.