4439-20-7

Basic information

• Product Name: N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE
• Synonyms: 2,2’-(1,2-ethanediyldiimino)bis-ethano;3,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE;2,2'-(ETHYLENEDIIMINO)DIETHANOL;2,2'-(ethane-1,2-diyldiimino)bisethanol;N,N'-Dihydroxyethyl-Ethylene Diamine;N,N'-Di-(2-Hydroxyethyl) Ethylenediamine;Curing agent No.2;2,2'-(1,2-Ethanediyldiimino)bisethanol
• CAS NO: 4439-20-7
• Molecular Formula: C₆H₁₆N₂O₂
• Molecular Weight: 148.2
• EINECS: 224-656-4
• Product Categories: intermediates;API
• Mol File: 4439-20-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 98-100 °C(lit.)
• Boiling Point: 268.81°C (rough estimate)
• Flash Point: 146.245 °C
• Appearance: White to pale yellow/Powder and/or Chunks
• Density: 1.0958 (rough estimate)
• Refractive Index: 1.4610 (estimate)
• PKA: 14.48±0.10(Predicted)
• Water Solubility: Soluble in water
• BRN: 1739630
• CAS DataBase Reference: N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE(4439-20-7)
• EPA Substance Registry System: N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE(4439-20-7)

Safety Data

• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3259 8/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 4439-20-7(Hazardous Substances Data)

Usage

Description

N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE, also known as BIS-2-(2-hydroxyethylamino)ethane, is a white crystalline powder with a unique chemical structure that features two hydroxyethylamine groups connected by an ethylene bridge. N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE exhibits interesting chemical properties, making it a versatile building block in various applications.

Uses

Used in Chemical Synthesis:
N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE is used as a chemical intermediate for the synthesis of various complex organic compounds. Its presence of two hydroxyethylamine groups allows for the formation of multiple types of chemical bonds, facilitating the creation of a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE is used as a precursor in the development of new drugs. Its unique structure can be modified to create novel therapeutic agents with potential applications in treating various diseases.
Used in Chelating Agents:
N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE is used as a chelating agent in various industrial processes. Its ability to form stable complexes with metal ions makes it useful in applications such as water treatment, where it can help remove heavy metals from contaminated water sources.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE is used as a functional ingredient in formulations. Its properties can contribute to the stability, solubility, and efficacy of various cosmetic products, enhancing their performance and consumer appeal.
Used in Research and Development:
N,N'-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE is also used in research and development settings, where it can serve as a model compound for studying chemical reactions and exploring new synthetic pathways. Its unique structure and reactivity make it a valuable tool for advancing scientific knowledge in various fields.

Upstream product

• 141-43-5 ethanolamine 
• 107-06-2 1,2-dichloro-ethane 
• 111-42-2 2,2'-iminobis[ethanol] 
• 107-15-3 ethylenediamine 
• 107-07-3 2-chloro-ethanol 
• 75-21-8 oxirane 
• 36697-72-0 4,4′,5,5′-Tetrahydro-2,2′-bioxazole 
• 111-41-1 2-(2-Aminoethylamino)ethanol 
• 123-91-1 1,4-dioxane 
• 112-67-4 n-hexadecanoyl chloride 
• 50-00-0 formaldehyd 
• 50-99-7 D-glucose 

Downstream Products

• 100261-48-1 N.N'-Bis-<2-hydroxy-aethyl>-N.N'-bis-<(4-chlor-phenyl)-thiocarbamoyl>-aethylendiamin 
• 100265-39-2 N.N'-Bis-<2-hydroxy-ethyl>-N.N'-bis-<(4-methoxy-phenyl)-thiocarbamoyl>-ethylendiamin 
• 101295-70-9 N.N'-Bis-<2-hydroxy-ethyl>-N.N'-bis-<(4-ethoxy-phenyl)-thiocarbamoyl>-ethylendiamin 
• 143065-57-0 4-tosyl-10,13-bis(2-hydroxyethyl)-1,7-dioxa-4,10,13-triazacyclopentadecane 
• 136949-86-5 3,6-bis(2,4-dinitrophenyl)-3,6-diazaoctane-1,8-diol 
• 56234-52-7 1,8-bis(p-toluenesulfonyloxy)-3,6-bis(p-toluenesulfonyl)-3,6-diazaoctane 
• 75173-44-3 1,4,7,10-tetraoxa-13,16-diazacyclooctadecane 
• 52601-74-8 N¹,N⁴,N⁷,N¹⁰,N¹³-pentatosyl-1,4,7,10,13-penta-azacyclopentadecane 
• 295-64-7 pentaaza-15-crown-5 
• 238099-16-6 N,N'-bis(2-acetyloxyethyl)-N,N'-bis-1,2-ethanediamine 
• 238099-20-2 N-(2-butyryloxyethyl)-N'-(2-hydroxyethyl)-N,N-bis-1,2-ethanediamine 
• 238099-17-7 N,N'-bis(2-propionyloxyethyl)-N,N'-bis-1,2-ethanediamine 
• 238099-21-3 N-(2-butyryloxyethyl)-N'-(2-ethyloxyethyl)-N,N-bis-1,2-ethanediamine 
• 238099-18-8 N,N'-bis(2-butyryloxyethyl)-N,N'-bis-1,2-ethanediamine 

Relevant articles and documents

Potentiometric and AM1d studies of the equilibria between silver(I) and diaza-15-crown and diaza-18-crown ethers with nitrogen in different positions in various solvents

Complex formation and stability constants between typical and atypical diaza-15-crown and diaza-18-crown ethers with silver(I) were determined in methanol, acetonitrile and propylene carbonate by the potentiometric method. In two of the diaza crown ethers, AA-diaza-15 and AA-diaza-18-crown, two nitrogens in the macrocyclic ring replaced two consecutive oxygens instead of two opposite ones in the two other diaza crown ethers. It was found that complexes of 1:1 and 1:2 metal-to-ligand stoichiometry were formed. The solvent composition and cavity size of crown ethers significantly influences the stability constants of complexes. AA-diaza-15 and AA-diaza-18-crown ethers were examined for comparison with diaza-15-crown and diaza-18-crown ethers. AA-diaza crown ethers formed less stable 1:1 metal-to-ligand complexes with silver(I) than typical diaza crown ethers but their ability to form 1:2 metal-to-ligand complexes was stronger. The energetically most favorable structures of the 1:1 metal-to-ligand complexes were calculated and visualized by the AM1d method at the semiempirical level of theory.

PROCESS FOR PREPARING EDFA AND/OR EDMFA AND DETA AND/OR TETA

A process for reacting ethylenediamine (EDA) with formaldehyde to give ethylenediamine-formaldehyde adduct (EDFA) and/or ethylenediamine-monoformaldehyde adduct (EDMFA), which comprises performing the reaction of FA with EDA at a temperature in the range from 20 to 70° C.

Ceramide-like compounds and a method for preparation thereof, and a cosmetic composition containing the same

Disclosed herein is a ceramide-like compound having properties of the natural ceramides, and a method for producing the same, and a cosmetic composition containing the same as a active ingredient.