444342-51-2Relevant articles and documents
Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents
Cheng, Jie-Fei,Huang, Yujin,Penuliar, Richard,Nishimoto, Masahiro,Liu, Larry,Arrhenius, Thomas,Yang, Guang,O'Leary, Eoin,Barbosa, Miguel,Barr, Rick,Dyck, Jason R. B.,Lopaschuk, Gary D.,Nadzan, Alex M.
, p. 4055 - 4058 (2007/10/03)
Discovery of 5-(1.1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5- dihydroisoxazole-3-carboxamides as a new class of malonyl-coenzyme A decarboxylase (MCD) inhibitors is described. tert-Butyl 3-(5-(1,1,1.3,3,3- hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroi