4452-11-3

Basic information

• Product Name: α-Benzoylstyrene
• Synonyms: 1,2-Diphenyl-2-propen-1-one;α-Benzoylstyrene;α-Phenylacrylophenone
• CAS NO: 4452-11-3
• Molecular Formula: C₁₅H₁₂O
• Molecular Weight: 208.26
• Mol File: 4452-11-3.mol
• Article Data: 56

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-Benzoylstyrene(CAS DataBase Reference)
• NIST Chemistry Reference: α-Benzoylstyrene(4452-11-3)
• EPA Substance Registry System: α-Benzoylstyrene(4452-11-3)

Safety Data

• Hazardous Substances Data: 4452-11-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 17, p. 809, 1987 DOI: 10.1080/00397918708063937

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 451-40-1 phenyl benzyl ketone 
• 50-00-0 formaldehyd 
• 55439-09-3 (Z)-3-hydroxy-1,2-diphenylprop-2-en-1-one 
• 5623-26-7 α-methylbenzoin 
• 186581-53-3 diazomethane 
• 72040-08-5 diphenylchloroazirine 
• 51-80-9 bis-(dimethylamino)methane 
• 2548-47-2 2,3-diphenyl-1,3-butadiene 
• 5431-88-9 4-benzoyltetrahydrofuran-2,3-dione 
• 3076-54-8 phenyllead(IV) triacetate 
• 7477-77-2 5,5-diphenyl-2(5H)-furanone 
• 75-18-3 dimethylsulfide 
• 98909-29-6 (1-Methoxy-1,2-diphenyl-2-propenyl)hydroperoxid 

Downstream Products

• 20451-28-9 1,2-diphenyl-3-piperidin-1-yl-propan-1-one 
• 32525-40-9 3-morpholin-4-yl-1,2-diphenyl-propan-1-one 
• 58338-01-5 (RS,SR)-1,2,4,5-tetraphenylpentane-1,5-dione 
• 16282-16-9 1,2-diphenyl-butan-1-one 
• 855365-41-2 1-(4-methoxy-phenyl)-2,4,5-triphenyl-pentane-1,5-dione 
• 21383-02-8 α-propyl deoxybenzoin 
• 4842-45-9 1,2,3-triphenylpropan-1-one 
• 92435-53-5 3-chloro-1,2-diphenylpropan-1-one 
• 7693-84-7 (1RS,2SR)-1,2-diphenyl-propan-1-ol 
• 86387-72-6 phenyl(2,5,6-triphenyl-3,4-dihydro-2H-pyran-2-yl)methanone 
• 22563-99-1 3-dimethylamino-1,2-diphenyl-propan-1-one 
• 2515-51-7 1,3,4-triphenyl-4,5-dihydro-1H-pyrazole 
• 855365-06-9 1-(4-chloro-phenyl)-2,4,5-triphenyl-pentane-1,5-dione 
• 40281-18-3 1,2-diphenyl-3-thiomorpholin-4-yl-propan-1-one 

Relevant articles and documents

β-Iodo Ketones by Prevost Reaction of Vinyl Carbinols

Treatment of α-ethenyl-α-phenylbenzenemethanol with iodine and silver acetate in either acetic acid or benzene gave 1,2-diphenyl-3-iodo-1-propanone (6) in 85percent yield.Ring enlargements involving similar rearrangements were observed with a number of cy

Specific alkylidene coupling of the labile diruthenium bridging methylene complex [(η-C5H5)2Ru2(μ-CH 2)(CO)2(MeCN)] with diazoalkanes (N2=CR2) giving alkenic products

Reaction of the labile diruthenium bridging methylene complex [(η-C5H5)2Ru2(μ-CH 2)(μ-CO)(CO)(MeCN)] with diazoalkanes (N2=CR1R2) results in specific C-C coupling to g

Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents

An enantioselective epoxidation of α-substituted vinyl ketones was realized to construct the key epoxide intermediates for the synthesis of various triazole antifungal agents. The reaction proceeded efficiently in high yields with good enantioselectivities by employing a chiral N,N′-dioxide/ScIII complex as the chiral catalyst and 35% aq. H2O2 as the oxidant. It enabled the facile transformation for optically active isavuconazole, efinaconazole, and other potential antifungal agents.

Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination

A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.