4457-72-1

Basic information

• Product Name: 1,5-DIBROMO-3-METHYLPENTANE
• Synonyms: 1,5-DIBROMO-3-METHYLPENTANE;3-METHYL-1,5-DIBROMOPENTANE;1,5-Dibromo-3-methylpentane,98%;1,5-dibromo-3-methylenepentane
• CAS NO: 4457-72-1
• Molecular Formula: C₆H₁₂Br₂
• Molecular Weight: 243.97
• Mol File: 4457-72-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 233℃
• Flash Point: 101°(214°F)
• Appearance: Clear colourless liquid
• Density: 1.6
• Vapor Pressure: 0.0896mmHg at 25°C
• Refractive Index: 1.508-1.51
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 1,5-DIBROMO-3-METHYLPENTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-DIBROMO-3-METHYLPENTANE(4457-72-1)
• EPA Substance Registry System: 1,5-DIBROMO-3-METHYLPENTANE(4457-72-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25
• Hazardous Substances Data: 4457-72-1(Hazardous Substances Data)

Usage

Description

1,5-Dibromo-3-methylpentane is an organic compound with the chemical formula C6H12Br2. It is a clear, colorless liquid at room temperature and is known for its unique chemical properties. 1,5-DIBROMO-3-METHYLPENTANE is primarily utilized in various industrial applications, including as a chemical reagent, pharmaceutical intermediate, and in pharmaceutical research.

Uses

1. Used in Chemical Synthesis:
1,5-Dibromo-3-methylpentane is used as a chemical reagent for the synthesis of various organic compounds. Its unique structure allows it to serve as a building block in the creation of complex molecules, making it a valuable asset in the field of organic chemistry.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,5-dibromo-3-methylpentane is employed as a pharmaceutical intermediate. It plays a crucial role in the development and production of various drugs, contributing to the advancement of medical treatments and therapies.
3. Used in Pharmaceutical Research:
1,5-Dibromo-3-methylpentane is also utilized in pharmaceutical research, where it aids in the investigation of new drug candidates and the study of their properties. Its unique chemical structure makes it an interesting subject for researchers looking to develop novel therapeutic agents.
4. Used in Solvent Applications:
Due to its liquid state at room temperature, 1,5-dibromo-3-methylpentane can be used as a solvent in various chemical processes. Its ability to dissolve a wide range of substances makes it a versatile option for a variety of applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C6H12Br2/c1-6(2-4-7)3-5-8/h6H,2-5H2,1H3

Upstream product

• 4457-71-0 3-methylpentane-1,5-diol 
• 17037-68-2 (4-methylpiperidin-1-yl)(phenyl)methanone 
• 4717-96-8 4-methyltetrahydropyran 
• 6829-42-1 diethyl 3-methylglutarate 
• 70928-41-5 5-methoxy-3-methyl-pentan-1-ol 
• 107-21-1 ethylene glycol 
• 4166-53-4 3-methylglutaric anhydride 
• 10138-44-0 2-ethoxy-4-methyl-3,4-dihydro-2H-pyran 
• 6280-15-5 3-methylpentanedial 

Downstream Products

• 10250-44-9 1-Brom-3-methyl-5-phthalimido-pentan 
• 5161-17-1 tetrahydro-4-methyl-2H-thiopyran 
• 54286-13-4 4-methyl-cyclohexane-1,1-dicarboxylic acid 
• 37518-69-7 1,1-diphenyl-4-methylphosphorinanium bromide 
• 524048-18-8 4-methylcyclohexane-1-carbonitrile 
• 101772-76-3 1,4-Dimethyl-1-phenyl-silinane 
• 101772-65-0 1,4-Dimethyl-1-phenyl-silinane 
• 51174-46-0 3-methyl-1,5-diiodopentane 
• 106683-06-1 22-methyltritetracontane 
• 66648-70-2 19-methylheptatriacontane 
• 139294-11-4 1,11-Ditosyloxy-2,6,10-trimethylundecane 
• 67512-92-9 4-methylthiane 1,1-dioxide 
• 38451-99-9 5-Methylcyclooctanon 
• 868609-70-5 (R)-3-methyl-2-(4-methyl-piperidin-1-yl)-butan-1-ol 

Relevant articles and documents

PHEROMONES OF INSECTS AND THEIR ANALOGS. XXIX. METHYL-BRANCHED PHEROMONES FROM 4-METHYLTETRAHYDROPYRAN. 4. SYNTHESIS OF (+/-)-15,19,23-TRIMETHYLHEPTATRIACONTANE - A PHEROMONE OF Glossina morsitans morsitans

Racemic 15,19,23-trimethylheptatriacontane (the sex pheromone of the tsetse fly Glossina morsitans morsitans) has been synthesized from 1,5-dibromo-3-methylpentane, a product of the acid hydrolysis of 4-methyltetrahydropyran.

Process intensification-assisted conversion of α,ω-alkanediols to dibromides

The increasingly widespread applications of α,ω-dibromides motivated development of a scalable, inexpensive process to rapidly convert selected α,ω-alkanediols to the corresponding dibromides. Diols were heated with only 48% aq HBr and an organic solvent, using a Dean-Stark apparatus modified to fractionate the azeotropic distillate, thereby maintaining a higher HBr concentration and reaction rate in the pot. Intensified distillation also increased the reaction rate. Various other substrate, solvent, and parameter effects have been discovered and rationalized.

Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S -methyltransferase 2

Betaine-homocysteine S-methyltransferase 2 (BHMT-2) catalyzes the transfer of a methyl group from S-methylmethionine to l-homocysteine, yielding two molecules of l-methionine. It is one of three homocysteine methyltransferases in mammals, but its overall contribution to homocysteine remethylation and sulfur amino acid homeostasis is not known. Moreover, recombinant BHMT-2 is highly unstable, which has slowed research on its structural and catalytic properties. In this study, we have prepared the first series of BHMT-2 inhibitors to be described, and we have tested them with human recombinant BHMT-2 that has been stabilized by copurification with human recombinant BHMT. Among the compounds synthesized, (2S,8RS,11RS)-5-thia-2,11-diamino-8-methyldodecanedioic acid (11) was the most potent (Kiapp ～77 nM) and selective inhibitor of BHMT-2. Compound 11 only weakly inhibited human BHMT (IC 50 about 77 μM). This compound (11) may be useful in future in vivo studies to probe the physiological significance of BHMT-2 in sulfur amino acid metabolism.