448184-56-3 Usage
Description
[2-([4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonylamino)ethyl]amino(oxo)acetic acid is a complex organic compound with a unique chemical structure. It is characterized by its sulfonyl and amino groups, as well as its oxoacetic acid backbone. [2-([4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonylamino)ethyl]amino(oxo)acetic acid has potential applications in various industries due to its specific chemical properties.
Uses
1. Used in Pharmaceutical Industry:
[2-([4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonylamino)ethyl]amino(oxo)acetic acid is used as an impurity in the synthesis of Vardenafil (V098001, 2HCl), a selective phosphodiesterase type 5 (PDE5) inhibitor. Its presence in the synthesis process is crucial for the development of Vardenafil, which is a medication used to treat erectile dysfunction and other related conditions.
2. Used in Chemical Research:
[2-([4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonylamino)ethyl]amino(oxo)acetic acid can be utilized in chemical research for studying its properties, reactivity, and potential applications in the development of new drugs or materials. Its unique structure may provide insights into the design of novel compounds with specific functions.
3. Used in Quality Control and Analysis:
[2-([4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonylamino)ethyl]amino(oxo)acetic acid can be employed as a reference compound in quality control and analytical processes. Its distinct chemical characteristics can be used to validate the performance of analytical instruments and methods, ensuring the accuracy and reliability of test results.
Check Digit Verification of cas no
The CAS Registry Mumber 448184-56-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,8,1,8 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 448184-56:
(8*4)+(7*4)+(6*8)+(5*1)+(4*8)+(3*4)+(2*5)+(1*6)=173
173 % 10 = 3
So 448184-56-3 is a valid CAS Registry Number.
448184-56-3Relevant articles and documents
Synthesis and spectral characterization of related substances of vardenafil, an erectile dysfunction drug
Reddy, Vajrala Venkata,Naga Brahmeswara Rao, Mandava Venkata,Reddy, Ghanta Mahesh,Mukkanti, Khagga,Reddy, Ganta Madhusudhan
, p. 3513 - 3523 (2012/10/18)
Vardenafil hydrochloride trihydrate (Levitra) is used to treat erectile dysfunction (ED) and is an inhibitor of phosphodiesterase type 5 (PDE-5) enzyme. It maintains higher levels of cyclic guanosine monophosphate (cGMP), relaxes smooth muscles, promotes penile blood flow, and enhances erectile function. During the bulk drug synthesis of vardenafil hydrochloride trihydrate, six related substances (impurities), vardenafil dimer, vardenafil N-oxide, vardenafil glycene, vardenafil oxopiperazine, vardenafil oxoacetic acid, and phenyl vardenafil were identified, and these are reported herein for the first time. The present work describes the synthesis and characterization of these impurities.
