4528-66-9

Basic information

• Product Name: Benzeneacetaldehyde, 4-methyl-a-(4-methylphenyl)-
• CAS NO: 4528-66-9
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 4528-66-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, 4-methyl-a-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, 4-methyl-a-(4-methylphenyl)-(4528-66-9)
• EPA Substance Registry System: Benzeneacetaldehyde, 4-methyl-a-(4-methylphenyl)-(4528-66-9)

Safety Data

• Hazardous Substances Data: 4528-66-9(Hazardous Substances Data)

Upstream product

• 2919-20-2 1,1-di(p-tolyl)ethylene 
• 93902-67-1 ethyl-(2,2-di-p-tolyl-vinyl)-ether 
• 129919-74-0 3,3-Bis(4-methylphenyl)-1,1-diphenylpropene 
• 75801-34-2 2,3-Di-p-tolyloxirane 
• 5173-28-4 1,2-di-p-tolylethane-1,2-diol 
• 859777-23-4 1,1-di-p-tolyl-ethane-1,2-diol 
• 940875-51-4 2-oxo-2-p-tolylethyl pivalate 
• 104-87-0 4-methyl-benzaldehyde 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 18869-29-9 (E)-4,4'-dimethylstilbene 
• 611-97-2 bis(p-methylphenyl)-methanone 
• 528856-86-2 4,4'-(2-methoxyethene-1,1-diyl)bis(methylbenzene) 
• 7647-01-0 hydrogenchloride 
• 22370-76-9 1,1-Aethylendioxy-2,2-di-p-tolylaethan 

Downstream Products

• 1588-49-4 4,4'-dimethylstilbene 
• 51490-06-3 1,2-di-p-tolyl-ethanone 
• 20809-78-3 bis-(4-methylphenyl)acetic acid 
• 25451-09-6 2,2-Di-p-tolyl-propane-1,3-diol 
• 159269-38-2 4,4-di(4-tolyl)butanoic acid 
• 528856-89-5 1,1-bis(4-tolyl)-2-iodoethane 
• 674334-53-3 3,3-bis(4-methylphenyl)-1-propene-1,1-dicarbonitrile 
• 528856-88-4 2,2-di-para-toluylethanol 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 

Relevant articles and documents

Method for preparing substituted carbonyl compound by catalyzing pinacol rearrangement reaction through molecular sieve

The invention discloses a method for preparing a substituted carbonyl compound by catalyzing pinacol rearrangement reaction through a molecular sieve. The method is characterized in that substituted pinacol as a substrate and toluene as solvent are subjected to a rearrangement reaction for 2-5h under the catalysis of an MCM-41, SBA-15, USY, Beta ZSM-5 or other aluminum-containing H-type acidic molecular sieve, the reaction temperature is 80-110 DEG C, the mass ratio of the substituted pinacol to the toluene to the catalyst is 100: 100: (10-50), the catalyst is filtered out after the reaction is finished, and purifying is performed to obtain a product, namely, the substituted carbonyl compound. Compared with the prior art, the method provided by the invention has the advantages of wide substrate application range, cheap catalyst, easy preparation, stability, no pollution to the environment, recyclability, realization of gram-scale preparation, and high reaction yield.

α,α-Diarylethylene Glycols as Valuable Precursor for Synthesis of 1,1-Diarylethenes and α,α-Diaryl Acetaldehydes

Towards assembling of diarylmethine unit present in biologically important molecules, we have developed a new Weinreb Amide (WA) based building block derived from glycolic acid. The WA functionality present in this building block permits the sequential addition of various arylmagnesium bromide reagents in a controlled manner that enables assembly of a diarylmethine unit. The developed synthetic route provides easy access to important diarylethenes and α,α-diarylethylene glycols. The synthesized α,α-diarylethylene glycols provide access to synthetically important symmetrical and unsymmetrical α,α-diaryl acetaldehydes as valuable intermediates.

Novel synthesis of α-arylnaphthalenes from diphenylacetaldehydes and 1,1-diphenylacetones

A two-step synthesis of 1-amino-4-arylnaphthalene-2-carbonitriles from diphenylacetaldehydes and 1,1-diphenylacetones involves condensation of the carbonyl compounds with malonodinitrile and cyclization of the aryl-ylidenemalonodinitriles obtained in conc