453547-85-8Relevant articles and documents
Imidazo[1,2-b]pyridazines: A potent and selective class of cyclin-dependent kinase inhibitors
Byth, Kate F.,Cooper, Nicola,Culshaw, Janet D.,Heaton, David W.,Oakes, Sandra E.,Minshull, Claire A.,Norman, Richard A.,Pauptit, Richard A.,Tucker, Julie A.,Breed, Jason,Pannifer, Andrew,Rowsell, Sian,Stanway, Judith J.,Valentine, Anna L.,Thomas, Andrew P.
, p. 2249 - 2252 (2004)
Modification of imidazo[1,2-a]pyridine CDK inhibitors lead to identification of less lipophilic imidazo[1,2-b]pyridazine series of CDK inhibitors. Although several equivalent compounds from these two series have similar structure and show similar CDK acti