454483-81-9 Usage
Description
4-Thiazolecarbonitrile, 2-(bromomethyl)is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by the presence of a thiazole ring, a carbonitrile group, and a bromomethyl group, which contribute to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-Thiazolecarbonitrile, 2-(bromomethyl)is used as a key intermediate in the preparation of 1,1-dioxido-4H-1,2,4-benzothiadiazines. These compounds have potential applications as hepatitis C polymerase inhibitors and anti-infective agents, making them valuable in the development of treatments for hepatitis C and other infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 454483-81-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,4,4,8 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 454483-81:
(8*4)+(7*5)+(6*4)+(5*4)+(4*8)+(3*3)+(2*8)+(1*1)=169
169 % 10 = 9
So 454483-81-9 is a valid CAS Registry Number.
454483-81-9Relevant articles and documents
MATRIPTASE INHIBITORS AND METHODS OF USE
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Page 47, (2010/02/07)
The present invention provides matriptase inhibitors and compositions thereof useful for treating cancer. Martripase is a trypsin-like serine protease active in the development of cancerous conditions, such as tumors and metastasis of cancer.
NEW COMPOUNDS
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Page 64, (2010/02/06)
The present invention relates to new compounds of formula I, wherein P Q X1 X2 X3 X4 X5 R R1 R2 R3 R4R5 G M1 M2 M3 m and n are defined as in formula I, a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.
