457-46-5

Basic information

• Product Name: 2-fluoro-N-phenylpropanamide
• CAS NO: 457-46-5
• Molecular Weight: 167.183
• Mol File: 457-46-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-fluoro-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-N-phenylpropanamide(457-46-5)
• EPA Substance Registry System: 2-fluoro-N-phenylpropanamide(457-46-5)

Safety Data

• Hazardous Substances Data: 457-46-5(Hazardous Substances Data)

Upstream product

• 21262-52-2 2-chloro-N-phenylpropanamide 
• 62-53-3 aniline 
• 2366-56-5 methyl 2-fluoropropanoate 
• 430-97-7 (R,S)-2-Fluoropropanoyl chloride 

Relevant articles and documents

Unbalanced-Ion-Pair-Catalyzed Nucleophilic Fluorination Using Potassium Fluoride

An unbalanced ion pair promoter (e.g., tetrabutylammonium sulfate), consisting of a bulky and charge-delocalized cation and a small and charge-localized anion, greatly accelerates nucleophilic fluorinations using easy handling KF. We also successfully converted an inexpensive and commercially available ion-exchange resin to the polymer-supported ion pair promoter (A26–SO42–), which could be reused after filtration. Moreover, A26–SO42– can be used in continuous flow conditions. In our conditions, water is well-tolerated.