457605-90-2

Basic information

• Product Name: 1-benzyl-2,2-di(2-propenyl)pyrrolidine
• Synonyms: 1-benzyl-2,2-di(2-propenyl)pyrrolidine
• CAS NO: 457605-90-2
• Molecular Weight: 241.376
• Mol File: 457605-90-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2,2-di(2-propenyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2,2-di(2-propenyl)pyrrolidine(457605-90-2)
• EPA Substance Registry System: 1-benzyl-2,2-di(2-propenyl)pyrrolidine(457605-90-2)

Safety Data

• Hazardous Substances Data: 457605-90-2(Hazardous Substances Data)

Upstream product

• 5291-77-0 1-benzyl-2-pyrrolidone 
• 1730-25-2 allylmagnesium bromide 
• 925-90-6 ethylmagnesium bromide 
• 144310-39-4 1-benzyl-5-methylsulfanyl-3,4-dihydro-2H-pyrrolium iodide 
• 40162-97-8 2,2-di(2-propenyl)pyrrolidine 
• 100-39-0 benzyl bromide 

Downstream Products

• 1017237-91-0 2,2-diallyl-1-benzylpyrrolidine hydrochloride 
• 100-42-5 styrene 
• 103-50-4 dibenzyl ether 
• 457605-92-4 1-benzyl-10-azaspiro[4.4]non-7-ene 
• 2622-14-2 tricyclohexylphosphine 

Relevant articles and documents

Tf2O/TTBP (2,4,6-Tri-tert-butylpyrimidine): An Alternative Amide Activation System for the Direct Transformations of Both Tertiary and Secondary Amides

Ten types of Tf2O/TTBP-mediated amide transformation reactions were investigated. The results showed that compared with pyridine derivatives 2,6-di-tert-butyl-4-methylpyridine (DTBMP) and 2-fluoropyridine (2-F-Pyr.), TTBP can serve as an alternative amide activation system for the direct transformation of both secondary and tertiary amides. For most surveyed examples, higher or comparable yields were generally obtained. In addition, Tf2O/TTBP combination was used to promote the condensation reactions of 2-(tert-butyldimethylsilyloxy)furan (TBSOF) with both tertiary and secondary amides, the one-pot reductive Bischler-Napieralski-type reaction of tertiary lactams, and Movassaghi and Hill's modern version of the Bischler-Napieralski reaction. The value of the Tf2O/TTBP-based methodology was further demonstrated by the concise and high-yielding syntheses of several natural products.

Direct, one-pot sequential reductive alkylation of lactams/amides with grignard and Organolithium reagents through lactam/amide activation

(Figure Presented) Be dazzled by the sequence: The first efficient and general one-pot method for the reductive bisalkylation of lactams/ amides with Grignard and organolithium reagents has been developed (see scheme; DTBMP = 2,6-di-tert-butyl-4methylpyridine, Tf=trifluoromethanesulfonyl).

Ring-closing metathesis of 2,2-diallyl derivatives of pyrrolidine and piperidine: a route to azaspiroheterocyclic structures

Transformations of 1-benzyl-2,2-di(2-propenyl)pyrrolidine and 1-benzyl-2,2-di(2-propenyl)piperidine into the corresponding 1-azaspiro[4.n]alkenes via ring-closing metathesis using accessible homogeneous catalytic systems WCl6-H2SiPh2, WOCl4-H2SiPh2, and R