459167-82-9

Basic information

• Product Name: 4-dimethylamino-4-[1-(4-oxo-pentyl)-cyclopropyl]-2,3-diphenyl-cyclopent-2-enone
• Synonyms: 4-dimethylamino-4-[1-(4-oxo-pentyl)-cyclopropyl]-2,3-diphenyl-cyclopent-2-enone
• CAS NO: 459167-82-9
• Molecular Weight: 401.549
• Mol File: 459167-82-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-dimethylamino-4-[1-(4-oxo-pentyl)-cyclopropyl]-2,3-diphenyl-cyclopent-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-dimethylamino-4-[1-(4-oxo-pentyl)-cyclopropyl]-2,3-diphenyl-cyclopent-2-enone(459167-82-9)
• EPA Substance Registry System: 4-dimethylamino-4-[1-(4-oxo-pentyl)-cyclopropyl]-2,3-diphenyl-cyclopent-2-enone(459167-82-9)

Safety Data

• Hazardous Substances Data: 459167-82-9(Hazardous Substances Data)

Upstream product

• 24400-75-7 ethylene-cetal de la bromo-5 pentanone-2 
• 459167-74-9 (4-ethoxy-1-{1-[3-(2-methyl-[1,3]dioxolan-2-yl)-propyl]-cyclopropyl}-2,3-diphenyl-cyclopenta-2,4-dienyl)-dimethyl-amine 
• 459167-53-4 trimethyl-{1-[3-(2-methyl-[1,3]dioxolan-2-yl)-propyl]-cyclopropylethynyl}-silane 
• 459167-54-5 2-[3-(1-ethynyl-cyclopropyl)-propyl]-2-methyl-[1,3]dioxolane 
• 81166-84-9 (2-cyclopropylethynyl)trimethylsilane 

Relevant articles and documents

Efficient syntheses of angularly fused triquinanes via β-amino-substituted α,β-unsaturated fischer-carbene complexes

Formal [3+2] cycloadditions of the carbene ligand in the new (3-dimethylamino-1-alkoxyalkenylidene)pentacarbonylchromium complexes 5 and 14 both with cyclopropyl substituents in the 3-position, onto alkynes give 5-dimethylamino-3-ethoxycyclopentadienes 6 and 15a-f, the latter along with regioisomers 16a-d, in good yields (55-72%). Treatment of these with hydrochloric acid liberates two carbonyl groups in each of them, and the resulting 5-dimethylaminocyclopent-1-en-3-ones 7 and 17a-c/18a-c, under basic conditions, undergo a cascade of two cyclizations, to yield angularly fused triquinanes 10 (68%) and 23a-c (30-97%). The overall procedure consists of four operational steps and produces cyclopropane-annelated tricyclo[6.3.0.01,5]undecane skeletons from two different alkynes each in 22-47% overall yield.