4603-58-1

Basic information

• Product Name: Thymidine
• Synonyms: Thymidine
• CAS NO: 4603-58-1
• Molecular Weight: 323.199
• Mol File: 4603-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thymidine(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine(4603-58-1)
• EPA Substance Registry System: Thymidine(4603-58-1)

Safety Data

• Hazardous Substances Data: 4603-58-1(Hazardous Substances Data)

Relevant articles and documents

Covalent alkylation of DNA with duocarmycin A. Identification of abasic site structure

Alkylation of d(CGTATACG) by antitumor antibiotic duocarmycin A was investigated. It was found that N3 of adenine6 (A6) attacks the cyclopropane subunit of duocarmycin A to produce covalently alkylated adduct 5. Upon heating (90 °C, 5 min) the adduct 5 decomposed to modified oligomer 1 with concomitant release of adenine adduct 2.