464192-28-7 Usage
Description
2-Bromo-5-fomylthiazole is an organic compound characterized by its yellow powder form. It is a derivative of thiazole, a heterocyclic compound with a broad range of applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2-Bromo-5-fomylthiazole is used as a reactant for the preparation of thienopyridines, which are potent checkpoint 1 kinase (CHK1) inhibitors. These inhibitors play a crucial role in the development of novel cancer therapeutics, as they help regulate cell cycle progression and DNA damage response, thus contributing to the prevention and treatment of various types of cancer.
Used in Chemical Synthesis:
Due to its unique chemical structure, 2-Bromo-5-fomylthiazole can be utilized as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and functional groups make it a valuable building block for creating complex molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 464192-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,4,1,9 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 464192-28:
(8*4)+(7*6)+(6*4)+(5*1)+(4*9)+(3*2)+(2*2)+(1*8)=157
157 % 10 = 7
So 464192-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H2BrNOS/c5-4-6-1-3(2-7)8-4/h1-2H
464192-28-7Relevant articles and documents
COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY
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Page/Page column 280, (2020/06/10)
In one aspect, compounds of Formula A, or a pharmaceutically acceptable salt thereof, are featured (Formula A) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.
Hetero-aromatic compound and its use in medicine
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Paragraph 1729; 1741-1742, (2019/07/04)
The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.
THIAZOLIDINONE DERIVATIVE
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Page/Page column 20, (2011/08/08)
An object of the present invention is to provide thiazolidinone derivatives. More specifically, an object of the present invention is to provide novel compounds having a CDC7 inhibitory action. The present invention provides thiazolidinone derivatives represented by the formula (I) The compounds of the present invention inhibit the CDC7 protein kinase activity, and suppress cell proliferation.