464917-79-1

Basic information

• Product Name: 4-phenylbutanoyl chloride
• Synonyms: 4-phenylbutanoyl chloride;(2Z)-3-Amino-2-butenoic acid phenylmethyl ester;benzyl (Z)-3-aminobut-2-enoate;2-Butenoic acid, 3-amino-, phenylmethyl ester, (2Z)-;ada@tuskwei.com sky
• CAS NO: 464917-79-1
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 182.64674
• Mol File: 464917-79-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 262.623°C at 760 mmHg
• Flash Point: 115.354°C
• Appearance: /
• Density: 1.109
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.522
• PKA: 5.28±0.70(Predicted)
• CAS DataBase Reference: 4-phenylbutanoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenylbutanoyl chloride(464917-79-1)
• EPA Substance Registry System: 4-phenylbutanoyl chloride(464917-79-1)

Safety Data

• Statements: R34:
• Safety Statements: S26-36/37/39-45:
• Hazardous Substances Data: 464917-79-1(Hazardous Substances Data)

Usage

General Description

4-phenylbutanoyl chloride is a chemical compound with the molecular formula C10H11ClO. It is a colorless to light yellow liquid with a pungent odor. 4-phenylbutanoyl chloride is commonly used as a reagent for the synthesis of various organic compounds, especially in the pharmaceutical and agrochemical industries. It is a versatile intermediate in the production of pharmaceuticals, flavorings, and fragrances. 4-phenylbutanoyl chloride is also used in the preparation of esters, amides, and other organic compounds through acylation reactions. It is important to handle this chemical with caution, as it is corrosive and can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C10H11ClO/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2

Upstream product

• 5396-89-4 benzyl acetoacetate 

Downstream Products

• 166809-88-7 3-(2-cyanoethoxycarbonyl)-5-(benzyloxycarbonyl)-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine 
• 915296-80-9 3-benzyl 5-ethyl 6-(chloromethyl)-4-(2,4-dichlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylate 

Relevant articles and documents

NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS

The present invention relates to novel dihydropyridine derivatives of formula (I): as modulators of nuclear receptors selected from androgen receptor and glucocorticoid receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of said for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by modulation of androgen receptor and/or glucocorticoid receptor, selected from cancer, metastasizing cancers, benign prostate hyperplasia, polycystic ovary syndrome (PCOS), hair loss, hirsutism, acne, hypogonadism, muscle wasting diseases, cachexia, Cushing's syndrome, anti-psychotic drug induced weight gain, obesity, post-traumatic stress disorder and alcoholism.

7,8-DIHYDRO-1,6-NAPHTHYDRIN-5(6H)-ONES AND RELATED BICYCLIC COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS

The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at leas

6-(((SUBSTITUTED)PYRIDIN-3-YL)ALKYL)-AND ALKENYL)-TETRAHYDRO-4-HYDROXYPYRAN-2-ONE INHIBITORS OF CHOLESTEROL BIOSYNTHESIS

Certain trans-6-[[(substituted)pyridin-3-yl]-alkyl-and alkenyl] tetrahydro-4-hydroxypyran-2-ones and the corresponding ring-opened acids derived therefrom are potent inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reducta