466-26-2

Basic information

• Product Name: Bullatine B
• Synonyms: Bullatine B;Aconitane-1,8,14-triol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-, (1-alpha,6-alpha,14-alpha,16-beta)-;Dideacetyldelphisine;Xuan-wu 3;Neoline,Bullatine B
• CAS NO: 466-26-2
• Molecular Formula: C₂₄H₃₉NO₆
• Molecular Weight: 437.573
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 466-26-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 153-154 °C
• Boiling Point: 578.3 °C at 760 mmHg
• Flash Point: 303.5 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 8.84E-16mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Methanol (Very Slightly)
• PKA: 13.32±0.70(Predicted)
• CAS DataBase Reference: Bullatine B(CAS DataBase Reference)
• NIST Chemistry Reference: Bullatine B(466-26-2)
• EPA Substance Registry System: Bullatine B(466-26-2)

Safety Data

• Hazardous Substances Data: 466-26-2(Hazardous Substances Data)

Usage

Uses

Bullatine B is an aconitine-type alkaloid which exhibits antiarrhythmic properties.

InChI:InChI=1/C24H39NO6/c1-5-25-10-22(11-29-2)7-6-15(26)24-13-8-12-14(30-3)9-23(28,16(13)18(12)27)17(21(24)25)19(31-4)20(22)24/h12-21,26-28H,5-11H2,1-4H3

Downstream Products

• 99633-05-3 14-benzoylneoline 
• 99633-08-6 neoline 1-benzoate 
• 99633-09-7 neoline 1,14-dibenzoate 
• 80665-72-1 15-β-hydroxyneoline 
• 80665-72-1 15-α-ydroxyneoline 

Relevant articles and documents

Unprecedented C19-diterpenoid alkaloid glycosides from an aqueous extract of “fu zi”: Neoline 14-O-L-arabinosides with four isomeric L-anabinosyls

Four structurally unprecedented aconitane-type C19-diterpenoid alkaloid glycosides with isomeric arabinosyls, named aconicarmichosides A–D (1–4), were isolated from an aqueous extract of “fu zi”, the lateral roots of Aconitum carmichaelii. Their structures were determined as neoline 14-O-α- and 14-O-β-L-arabinopyranosides (1 and 2) and 14-O-α- and 14-O-β-L-arabinofuranosides (3 and 4), by spectroscopic and chemical methods including 2D NMR experiments and acid hydrolysis. Compounds 1–4 represent the first examples of glycosidic diterpenoid alkaloids.