4693-91-8 Usage
Description
4-Methoxyphenylacetyl chloride is an organic compound with the chemical formula C8H7ClO3. It is a derivative of acetyl chloride, featuring a 4-methoxyphenyl group attached to the acetyl moiety. 4-Methoxyphenylacetyl chloride is a versatile intermediate in organic synthesis and has potential applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Synthesis:
4-Methoxyphenylacetyl chloride is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity and functional groups make it suitable for the preparation of a wide range of drugs and drug candidates.
Used in the Synthesis of Substituted Spiro[4.5]decane:
In the chemical industry, 4-Methoxyphenylacetyl chloride is used as a building block for the synthesis of substituted spiro[4.5]decane compounds. These complex organic molecules have potential applications in various fields, including materials science and medicinal chemistry.
Used in the Synthesis of 1-(4′-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline (Higenamine):
4-Methoxyphenylacetyl chloride is utilized as a starting material in the production of higenamine, a cardiotonic principle found in aconite root. Higenamine has potential therapeutic applications in the treatment of heart conditions due to its ability to strengthen cardiac contractions.
Used in the Synthesis of 2,5-Naphthyridine:
4-Methoxyphenylacetyl chloride is employed as a reactant in the synthesis of 2,5-naphthyridine, a heterocyclic compound with potential applications in medicinal chemistry and as a building block for the development of new pharmaceutical agents.
Used in the Synthesis of (R)-(+)-Nor-Roefractine:
In the field of asymmetric synthesis, 4-Methoxyphenylacetyl chloride is used as a chiral precursor for the preparation of (R)-(+)-norroefractine, an optically active compound with potential applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 4693-91-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,9 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4693-91:
(6*4)+(5*6)+(4*9)+(3*3)+(2*9)+(1*1)=118
118 % 10 = 8
So 4693-91-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO2/c1-12-8-4-2-7(3-5-8)6-9(10)11/h2-5H,6H2,1H3
4693-91-8Relevant articles and documents
Total synthesis of two isoflavone C-glycosides (6-tert-butyl puerarin and 6-tert-butyl-4′-methoxypuerarin) through the deoxybenzoin pathway
Zou, Yunpeng,Zhang, Shouguo,Wen, Xiaoxue,wang, Gang,sun, Yunbo,Liu, Shuchen,Peng, Tao,Gao, Yue,Wang, Lin
, p. 2835 - 2837 (2017)
The total synthesis of two isoflavone C-glycosides (6-tert-butylpuerarin and 6-tert-butyl-4′-methoxypuerarin) was achieved through the deoxybenzoin pathway with overall yields of 14.6% and 14.2%. The key intermediate 12 was obtained by de-tert-butylation
R - alpha - amino -4 - methoxybenzene b amide synthesis method
-
Page/Page column 5-8, (2019/03/28)
The invention relates to a preparing method of a compound, in particular to a compounding method of R-alpha-amino-4-anisyl phenyl acetamide, which comprises the following steps: acidylation, methylation and aminolysis. In the step of acidylation, raw mate
Diastereoselective Electrophilic Trifluoromethylthiolation of Chiral Oxazolidinones: Access to Enantiopure α-SCF3 Alcohols
Chachignon, Hélène,Kondrashov, Evgeniy V.,Cahard, Dominique
supporting information, p. 965 - 971 (2018/01/27)
Lithium imide enolates featuring Evans’ chiral oxazolidinone auxiliary were involved in diastereoselective α-trifluoromethylthiolation with electrophilic SCF3 donors. Diastereopure products were isolated and converted to enantiopure α-SCF3 alcohols without racemisation. (Figure presented.).