470699-97-9

Basic information

• Product Name: 5'-O-benzyl-2'-deoxy-3'-O-diethylphosphoryl-4'α-[(2-iodophenylethylthio)carbonyl]thymidine
• CAS NO: 470699-97-9
• Molecular Weight: 758.568
• Mol File: 470699-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-benzyl-2'-deoxy-3'-O-diethylphosphoryl-4'α-[(2-iodophenylethylthio)carbonyl]thymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-benzyl-2'-deoxy-3'-O-diethylphosphoryl-4'α-[(2-iodophenylethylthio)carbonyl]thymidine(470699-97-9)
• EPA Substance Registry System: 5'-O-benzyl-2'-deoxy-3'-O-diethylphosphoryl-4'α-[(2-iodophenylethylthio)carbonyl]thymidine(470699-97-9)

Safety Data

• Hazardous Substances Data: 470699-97-9(Hazardous Substances Data)

Upstream product

• 177748-62-8 2-(2-iodophenyl)-1-ethanethiol 
• 208175-42-2 5'-O-benzyl-3'-O-(tert-butyldimethylsilyl)-2'-deoxy-4'α-methoxycarbonyl-D-thymidine 
• 470699-77-5 5'-O-benzyl-4'α-carboxyl-2'-deoxythymidine 
• 470699-78-6 5'-O-benzyl-2'-deoxy-4'α-[(2-iodophenylethylthio)carbonyl]thymidine 

Downstream Products

• 4565-32-6 2,3-dihydrobenzo(b)thiophene 

Relevant articles and documents

The effect of the base in the fragmentation of nucleotide C4′ radicals

A series of 3′-O-diethylphosphoryl-4′-α-[(2-halophenylethylthio) carbonyl] substituted esters of thymidine, cytidine, adenosine and guanosine are prepared by total synthesis and used as C4′-radical precursors in a competition kinetic method using tributyltin hydride as the reductant. The pseudo-first order rate constants for the C4′-radicals so generated decrease in the order guansoine>cytidine>adenosine>thymidine with that for guanosine being too rapid for determination by the present competition kinetic method. A 119Sn NMR method is presented for estimation of the purity of tin hydride solutions.