4733-69-1

Basic information

• Product Name: furo[3,4-b]pyridin-5(7H)-one
• Synonyms: 5H,7H-furo[3,4-b]pyridin-5-one;7-Azaphthalide;Furo[3,4-b]pyridin-7(5H)-one;5H-Furo[3,4-b]pyridin-7-one
• CAS NO: 4733-69-1
• Molecular Formula: C₇H₅NO₂
• Molecular Weight: 135
• EINECS: -0
• Mol File: 4733-69-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 164℃
• Boiling Point: 330.9°C at 760 mmHg
• Flash Point: 153.9°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 0.000161mmHg at 25°C
• Refractive Index: 1.592
• CAS DataBase Reference: furo[3,4-b]pyridin-5(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: furo[3,4-b]pyridin-5(7H)-one(4733-69-1)
• EPA Substance Registry System: furo[3,4-b]pyridin-5(7H)-one(4733-69-1)

Safety Data

• Hazardous Substances Data: 4733-69-1(Hazardous Substances Data)

Usage

General Description

Furo[3,4-b]pyridin-5(7H)-one is a chemical compound with a fused heterocyclic structure containing a furan and a pyridine ring. It is also known as 6H-furo[3,4-b]pyridin-5-one and has a molecular formula C6H5NO. furo[3,4-b]pyridin-5(7H)-one has been identified as a key intermediate in the synthesis of potential bioactive molecules, including pharmaceuticals and agrochemicals. Furo[3,4-b]pyridin-5(7H)-one has attracted interest in the scientific community due to its versatile reactivity and potential applications in medicinal and agricultural chemistry. Research on this compound aims to explore its pharmacological and pesticidal properties to develop new and more effective drugs and crop protection products.

InChI:InChI=1/C7H5NO2/c9-7-5-2-1-3-8-6(5)4-10-7/h1-3H,4H2

Upstream product

• 89-00-9 Pyridine-2,3-dicarboxylic acid 
• 108-24-7 acetic anhydride 
• 4663-93-8 pyridine-2,3-dicarbaldehyde 
• 38070-79-0 2,3-bis(hydroxymethyl)pyridine 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 

Downstream Products

• 81675-17-4 (1-Benzenesulfonyl-1H-indol-2-yl)-(3-hydroxymethyl-pyridin-2-yl)-methanone 
• 693271-27-1 3-[(4-methoxyphenoxy)methyl]pyridine-2-carboxylic acid 
• 55942-66-0 3-(phenoxymethyl)pyridine-2-carboxylic acid 
• 216658-54-7 3-(3-Chloro-phenoxymethyl)-pyridine-2-carboxylic acid 
• 1311295-61-0 benzyl 3-(((tert-butyldimethylsilyl)oxy)methyl)picolinate 
• 1311295-63-2 C₂₁H₃₄N₂O₄Si 
• 1311295-67-6 C₃₀H₄₇N₃O₇Si₂ 
• 1311295-60-9 C₁₄H₁₃NO₃ 

Relevant articles and documents

Efficient and Selective Cu/Nitroxyl-Catalyzed Methods for Aerobic Oxidative Lactonization of Diols

Cu/nitroxyl catalysts have been identified that promote highly efficient and selective aerobic oxidative lactonization of diols under mild reaction conditions using ambient air as the oxidant. The chemo- and regioselectivity of the reaction may be tuned by changing the identity of the nitroxyl cocatalyst. A Cu/ABNO catalyst system (ABNO = 9-azabicyclo[3.3.1]nonan-N-oxyl) shows excellent reactivity with symmetrical diols and hindered unsymmetrical diols, whereas a Cu/TEMPO catalyst system (TEMPO = 2,2,6,6-tetramethyl-1-piperidinyl-N-oxyl) displays excellent chemo- and regioselectivity for the oxidation of less hindered unsymmetrical diols. These catalyst systems are compatible with all classes of alcohols (benzylic, allylic, aliphatic), mediate efficient lactonization of 1,4-, 1,5-, and some 1,6-diols, and tolerate diverse functional groups, including alkenes, heterocycles, and other heteroatom-containing groups.

Dual fluorescent N-Aryl-2,3-naphthalimides: Applications in ratiometric DNA detection and white organic light-emitting devices

A ten element matrix of 5- and 6-substituted-(2,3)-naphthalimides was prepared for the appropriate placement of substituents necessary to promote dual fluorescence (DF). As prescribed by our balanced seesaw photophysical model this matrix yielded nine new DF dyes out of a possible ten compounds. From this set of nine DF dyes, 4-fluoronaphthalic amide (37) was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.