474538-99-3

Basic information

• Product Name: 1'-benzylspiro[indoline-3,4'-piperidine]
• Synonyms: 1'-benzylspiro[indoline-3,4'-piperidine];1,2-dihydro-1'-(phenylmethyl)-Spiro[3H-indole-3,4'-piperidine];1'-benzyl-1,2-dihydrospiro[indole-3,4'-piperidine];1'-benzylspiro[1,2-dihydroindole-3,4'-piperidine]
• CAS NO: 474538-99-3
• Molecular Formula: C₁₉H₂₂N₂
• Molecular Weight: 278.397
• Mol File: 474538-99-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1'-benzylspiro[indoline-3,4'-piperidine](CAS DataBase Reference)
• NIST Chemistry Reference: 1'-benzylspiro[indoline-3,4'-piperidine](474538-99-3)
• EPA Substance Registry System: 1'-benzylspiro[indoline-3,4'-piperidine](474538-99-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 474538-99-3(Hazardous Substances Data)

Usage

General Description

1'-benzylspiro[indoline-3,4'-piperidine] is a chemical compound with a spirocyclic structure that consists of a spiro[indoline-3,4'-piperidine] core with a benzyl group attached at the 1' position. It is used in the synthesis of various pharmaceuticals and biologically active molecules due to its unique structural features. 1'-benzylspiro[indoline-3,4'-piperidine] has been studied for its potential pharmacological properties, including its role as an anti-inflammatory, analgesic, and anti-tumor agent. Additionally, 1'-benzylspiro[indoline-3,4'-piperidine] has shown potential as a dopaminergic and serotoninergic ligand, making it a candidate for the development of new drugs targeting the central nervous system. Its diverse range of pharmacological activities makes it an important compound for further research and potential drug development.

Upstream product

• 22065-85-6 N-benzyl-4-formylpiperidine 
• 100-63-0 phenylhydrazine 

Downstream Products

• 867009-74-3 C₂₄H₃₀N₂O₂ 

Relevant articles and documents

SUBSTITUTED DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES AND THEIR USE AS NEUROKININ ANTAGONISTS

This invention concerns substituted diaza-spiro-[4.5]-decane derivatives having neurokinin antagonistic activity, in particular NK1 antagonistic activity, a combined NK1/NK2 antagonist ic activity, a combined NK1/NK3 antagonist ic activity and a combined NK1/NK2/NK3 antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment and/or prophylaxis of schizophrenia, emesis, anxiety and depression, irritable bowel syndrome (IBS), circadian rhythm disturbances, pre-eclampsia, nociception, pain, in particular visceral and neuropathic pain, pancreatitis, neurogenic inflammation, asthma, chronic obstructive pulmonary disease (COPD) and micturition disorders such as urinary incontinence. The compounds according to the invention can be represented by general Formula (I) and comprises also the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the N-oxide form thereof and prodrugs thereof, wherein all substituents are defined as in Claim 1.