475105-77-2

Basic information

• Product Name: 2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid
• Synonyms: 2-(3-METHYL-1,2,4-OXADIAZOL-5-YL)BENZOIC ACID;5-(2-Carboxyphenyl)-3-methyl-1,2,4-oxadiazole
• CAS NO: 475105-77-2
• Molecular Formula: C₁₀H₈N₂O₃
• Molecular Weight: 204.18212
• Mol File: 475105-77-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 152 °C
• Boiling Point: 409.9°Cat760mmHg
• Flash Point: 201.7°C
• Appearance: /
• Density: 1.336g/cm³
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid(475105-77-2)
• EPA Substance Registry System: 2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid(475105-77-2)

Safety Data

• Hazardous Substances Data: 475105-77-2(Hazardous Substances Data)

Usage

General Description

2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid is a chemical compound with the molecular formula C10H8N2O3. It is a derivative of benzoic acid, containing a 1,2,4-oxadiazole ring substituted with a methyl group. 2-(3-Methyl-1,2,4-oxadiazol-5-yl)benzoic acid has potential applications in pharmaceuticals, agrochemicals, and materials science due to its unique chemical structure and properties. It may have biological activity and can be used as a building block in the synthesis of various compounds. Its specific uses and properties would depend on the context and the intended application.

InChI:InChI=1/C10H8N2O3/c1-6-11-9(15-12-6)7-4-2-3-5-8(7)10(13)14/h2-5H,1H3,(H,13,14)

Upstream product

• 4387-36-4 2-iodobenzonitrile 
• 1283108-04-2 5-(2-iodophenyl)-3-methyl-1,2,4-oxadiazole 

Downstream Products

• 1293940-64-3 tert-butyl (1S,6R)-8-(2-(3-methyl-1,2,4-oxadiazol-5-yl)benzoyl)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate 
• 1293938-83-6 3-(4,6-dimethylpyrimidin-2-yl)-8-{[2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]carbonyl}-(1S,6R)-3,8-diazabicyclo[4.2.0]octane 
• 1293938-92-7 4-(dimethylamino)-6-[8-{[2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]carbonyl}-(1S,6R)-3,8-diazabicyclo[4.2.0]oct-3-yl]pyrimidine 
• 1293940-61-0 (1S,6R)-3,8-diazabicyclo[4.2.0]octan-8-yl(2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)methanone 
• 1604794-65-1 methyl 4-cyano-2-{[(3R,6R)-6-methyl-1-{[2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]carbonyl}piperidin-3-yl]oxy}pyridine-3-carboxylate 

Relevant articles and documents

6,5-BICYCLIC OCTAHYDROPYRROLOPYRIDINE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to 6,5-bicyclic octahydropyrrolopyridine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

PYRROLIDINE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to pyrrolidine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.