477515-22-3

Basic information

• Product Name: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-(4-nitrobenzylidene)acetohydrazide
• Synonyms: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-(4-nitrobenzylidene)acetohydrazide
• CAS NO: 477515-22-3
• Molecular Weight: 352.306
• Mol File: 477515-22-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-(4-nitrobenzylidene)acetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-(4-nitrobenzylidene)acetohydrazide(477515-22-3)
• EPA Substance Registry System: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-(4-nitrobenzylidene)acetohydrazide(477515-22-3)

Safety Data

• Hazardous Substances Data: 477515-22-3(Hazardous Substances Data)

Upstream product

• 6974-10-3 phthalimidoacetic acid ethyl ester 
• 6780-38-7 N-phthaloylglycine chloride 
• 4702-13-0 N-phthaloylglycine 
• 85-44-9 phthalic anhydride 
• 40868-97-1 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetohydrazide 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

Synthesis of new 5-aryl tetrazoline from N-aceto hydrazide cyclic imides and study of biological activity

The research resulted in the production of new tetrazoline derivatives. Firstly; the reaction of N-acetyl chloro cyclic imides with hydrazine hydrate to give compounds (1,2). Then, compounds (1,2) were reacted with different aromatic aldehydes to give Schiff bases (3-10). The compounds of N-( 2-chloro acetyl) cyclic imides were reacted with sodium azide to give N- (azido acetyl) cyclic imides (11,12). Finally, the reaction of the prepared Schiff bases compounds with azide compounds and cyclization to give 5-aryl tetrazoline on cyclic imides (13-20). The prepared compounds were characterized by FT-IR and some of them by 1H NMR, melting point, and were studied the effects of the preparing compounds on some strains of bacteria and fungi.