477845-12-8 Usage
Description
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine, also known as Pim-1 Inhibitor 2, is a potent small molecule inhibitor that targets the serine/threonine kinase Pim-1. 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine plays a crucial role in cell survival and proliferation, and its dysregulation has been implicated in tumorigenesis. Pim-1 Inhibitor 2 specifically targets the ATP-binding kinase hinge region, making it a promising candidate for various pharmaceutical applications.
Uses
Used in Anticancer Applications:
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine is used as an anti-tumor agent for its ability to inhibit the serine/threonine kinase Pim-1, which is involved in cell proliferation and survival. By targeting this kinase, Pim-1 Inhibitor 2 has the potential to disrupt the processes that contribute to tumor growth and development, making it a valuable tool in the fight against cancer.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine is used as a potent Pim-1 inhibitor for the development of novel therapeutic strategies against cancer. Its high affinity for the ATP-binding kinase hinge region allows researchers to study the effects of Pim-1 inhibition on various cancer cell lines and explore its potential as a targeted treatment option.
Used in Drug Design and Development:
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine is also used in the field of drug design and development as a lead compound for the creation of new Pim-1 inhibitors. Its structure and activity provide valuable insights into the design of more effective and selective inhibitors, which could lead to the development of improved cancer treatments with fewer side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 477845-12-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,7,8,4 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 477845-12:
(8*4)+(7*7)+(6*7)+(5*8)+(4*4)+(3*5)+(2*1)+(1*2)=198
198 % 10 = 8
So 477845-12-8 is a valid CAS Registry Number.
