478038-18-5

Basic information

• Product Name: Benzoic acid, 4-chloro-, 2-[(bicyclo[2.2.1]hept-5-en-2-ylamino)thioxomethyl]hydrazide
• CAS NO: 478038-18-5
• Molecular Formula: C15H16ClN3OS
• Molecular Weight: 321.831
• Mol File: 478038-18-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-chloro-, 2-[(bicyclo[2.2.1]hept-5-en-2-ylamino)thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-chloro-, 2-[(bicyclo[2.2.1]hept-5-en-2-ylamino)thioxomethyl]hydrazide(478038-18-5)
• EPA Substance Registry System: Benzoic acid, 4-chloro-, 2-[(bicyclo[2.2.1]hept-5-en-2-ylamino)thioxomethyl]hydrazide(478038-18-5)

Safety Data

• Hazardous Substances Data: 478038-18-5(Hazardous Substances Data)

Upstream product

• 92819-45-9 bicyclo[2.2.1]hept-5-en-2-ylisothiocyanate 
• 536-40-3 4-chlorobenzoic acid hydrazide 

Relevant articles and documents

4-substituted-1- (arylmethylidene) thiosemicarbazide, 4-substituted-1- (arylcarbonyl) thiosemicarbazide and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to optionally substituted 4-substituted-1-(arylmethylidene)thiosemicarbazide, 4-substituted-1-(arylcarbonyl)thiosemicarbazide and analogs thereof, represented by the Formulae I and II: wherein A1, A2, Q and R1-R3 are defined herein. The present invention also relates to the discovery that compounds having Formulae I and II are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.